CLOSTRIDIOIDES DIFFICILE INFECTION

This study is testing if adding a fecal microbiota transplant (FMT) to standard antibiotic treatment works better than antibiotics alone to cure a first or second C. diff infection and prevent it from coming back. It will involve 220 adults who have a new C. diff infection or the…

This study is testing if a single dose of an investigational drug called AZD5148 can prevent C. difficile infection from coming back after a person has just been treated for it. About 230 adults who have recently finished antibiotic treatment for a C. diff infection will receive …

This early-stage trial is testing a new probiotic pill called EXL01. It aims to prevent dangerous C. difficile infections from coming back in patients who are at high risk of recurrence. The study will compare the pill to a placebo in 56 patients to see if it's safe and if it can…

This study is testing an investigational drug called LMN-201 to see if it can prevent a C. difficile (C. diff) infection from coming back after a person finishes their standard antibiotic treatment. The trial will enroll 375 adults who have recently been diagnosed with C. diff an…

This study aims to prevent repeat Clostridioides difficile (C. diff) infections in people who recently had one and need to take antibiotics again. It will test if taking oral vancomycin (an antibiotic) alongside the new antibiotic course can protect the gut and stop C. diff from …

This study is testing whether a 14-day course of an investigational oral drug called VE303 can prevent a C. difficile infection from coming back after standard antibiotic treatment. It will enroll 852 people who have just been treated for a C. diff infection and are at high risk …

This study aims to understand why some treatments for C. difficile infection work better than others. Researchers will observe 200 patients receiving either standard antibiotics or a fecal microbiota transplant (FMT) as part of their normal care. They will collect samples and sur…