CLOSTRIDIOIDES DIFFICILE INFECTION
Clinical trials for CLOSTRIDIOIDES DIFFICILE INFECTION explained in plain language.
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Gut bacteria capsules take on superbugs in antibiotic patients
Disease control CompletedThis study tested whether taking capsules containing healthy gut bacteria could help clear drug-resistant germs (including C. difficile) from the intestines of 42 hospitalized adults who needed at least 7 days of antibiotics. Participants received either the bacteria capsules or …
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Phase: PHASE1, PHASE2 • Sponsor: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New antibiotic CRS3123 takes on c. diff in early trial
Disease control CompletedThis phase 2 study tested an experimental antibiotic called CRS3123 against the standard treatment vancomycin for Clostridioides difficile infection (C. diff). 43 adults with a first episode or first recurrence of C. diff took either CRS3123 or vancomycin for 10 days. The main go…
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Phase: PHASE2 • Sponsor: Crestone, Inc • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New drug combo shows promise against deadly gut infection
Disease control CompletedThis study tested whether adding the drug bezlotoxumab to standard treatment could prevent serious outcomes in people with a severe C. diff infection. Researchers used a special score to identify 44 high-risk patients. The goal was to see if the drug reduced organ failure, infect…
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Phase: PHASE2 • Sponsor: Hellenic Institute for the Study of Sepsis • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Early safety check for new c. diff drug in japanese volunteers
Knowledge-focused CompletedThis early-stage study tested a single dose of AZD5148, a potential treatment for C. difficile infection, in 16 healthy Japanese adults. The main goal was to see if the drug is safe and how the body processes it. Participants received either the drug or a placebo by injection and…
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Phase: PHASE1 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Tiny study aims to improve c. diff sample collection
Knowledge-focused CompletedThis study looked at how well stool and blood samples could be collected from 7 adults with an active C. diff infection. Researchers wanted to see if the collection, shipping, and testing methods worked smoothly. Participants also filled out questionnaires about their symptoms. T…
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC