New drug shows promise in fighting deadly gut infection
NCT ID NCT05304715
First seen Mar 21, 2026 · Last updated May 15, 2026 · Updated 8 times
Summary
This study tested whether adding the drug bezlotoxumab to standard treatment could help people with a serious gut infection called C. diff. The trial included 44 adults at high risk for complications like organ failure, relapse, or death. Researchers used a special score to identify these patients and gave them either bezlotoxumab or a placebo to see if the drug reduced these bad outcomes by day 40.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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1st Department of Internal Medicine, AHEPA University General Hospital of Thessaloniki
Thessaloniki, 54621, Greece
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1st Department of Internal Medicine, General University Hospital of Ioannina
Ioannina, 45500, Greece
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1st Department of Internal Medicine, THRIASIO General Hospital of Eleusis
Athens, 10918, Greece
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1st University Department of Internal Medicine, LAIKO General Hospital of Athens,
Athens, 11527, Greece
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1st University Department of Propaedeutic Surgery, IPPOKRATEION General Hospital
Athens, 11527, Greece
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2nd Department of Internal Medicine, Thriasio General Hospital
Athens, 10918, Greece
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2nd Department of Internal Medicine, Tzanneion General Hospital
Piraeus, 18536, Greece
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2nd Department of Internal Medicine, University General Hospital of Alexandroupolis
Alexandroupoli, 68100, Greece
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4th Department of Internal Medicine, Attikon University Hospital
Athens, 12462, Greece
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Department of Internal Medicine, Larissa University Hospital
Larissa, 41334, Greece
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Department of Internal Medicine, University General Hospital of Patras PANAGIA I VOITHIA
Pátrai, 26504, Greece
Conditions
Explore the condition pages connected to this study.