Could a single friendly gut bacterium prevent recurrent c. diff?
NCT ID NCT06306014
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests EXL01, a single strain of a beneficial gut bacterium (Faecalibacterium prausnitzii), to see if it can prevent repeat Clostridioides difficile infections in people at high risk. About 56 adults who have had at least two C. diff episodes will take EXL01 or a placebo by mouth. The goal is to see if this treatment is safe and reduces the chance of another infection at 8 weeks.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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APHM La Timone Service de Maladies infectieuses
RECRUITINGMarseille, France
Contact Email: •••••@•••••
Contact
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CH Annecy Genevois Service de Maladies infectieuses
NOT_YET_RECRUITINGAnnecy, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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CHU Grenoble Service Maladies infectieuses et tropicales
NOT_YET_RECRUITINGGrenoble, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Service d'Hépato-gastroentérologie Hôpital de la Croix Rousse
RECRUITINGLyon, 69004, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Service d'hépato-gastroentérologie - CHU Estaing
RECRUITINGClermont-Ferrand, 63003, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Service d'hépato-gastroentérologie - Hôpital Saint Antoine (APHP)
RECRUITINGParis, 75012, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Service d'infectiologie - Hôpital Nord / CHU Saint Etienne
NOT_YET_RECRUITINGSaint-Etienne, 42100, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Service de Maladies Infectieuses - CH de Valence
RECRUITINGValence, 26000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Service de médecine interne - Pôle des maladies de l'appareil digestif - CHU de Toulouse
RECRUITINGToulouse, 31059, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact