Could a single friendly gut bug prevent c. diff from coming back?

NCT ID NCT06306014

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 31 times

Summary

This study tests a new treatment called EXL01, which contains a single type of beneficial gut bacteria (Faecalibacterium prausnitzii), to see if it can prevent repeat Clostridioides difficile infections in people at high risk. About 56 adults who have had at least two or three C. diff episodes will take EXL01 or a placebo by mouth. The goal is to see if this approach is safe and reduces the chance of another infection at 8 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APHM La Timone Service de Maladies infectieuses

    RECRUITING

    Marseille, France

    Contact Email: •••••@•••••

    Contact

  • CH Annecy Genevois Service de Maladies infectieuses

    NOT_YET_RECRUITING

    Annecy, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU Grenoble Service Maladies infectieuses et tropicales

    NOT_YET_RECRUITING

    Grenoble, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Service d'Hépato-gastroentérologie Hôpital de la Croix Rousse

    RECRUITING

    Lyon, 69004, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Service d'hépato-gastroentérologie - CHU Estaing

    RECRUITING

    Clermont-Ferrand, 63003, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Service d'hépato-gastroentérologie - Hôpital Saint Antoine (APHP)

    RECRUITING

    Paris, 75012, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Service d'infectiologie - Hôpital Nord / CHU Saint Etienne

    NOT_YET_RECRUITING

    Saint-Etienne, 42100, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Service de Maladies Infectieuses - CH de Valence

    NOT_YET_RECRUITING

    Valence, 26000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Service de médecine interne - Pôle des maladies de l'appareil digestif - CHU de Toulouse

    RECRUITING

    Toulouse, 31059, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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