CLEFT PALATE
Clinical trials for CLEFT PALATE explained in plain language.
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New jaw expander could improve smiles for kids with cleft lip and palate
Disease control CompletedThis study tested a new device called the Leaf Self Expander to widen the upper jaw in 20 children with cleft lip and palate. The device was compared to the standard rapid maxillary expander. Researchers used 3D scans to measure changes in bone and tooth position. The goal was to…
Matched conditions: CLEFT PALATE
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Fat graft patch boosts palate hole repair in cleft patients
Disease control CompletedThis study tested a new surgical technique for repairing a common complication after cleft palate surgery: a hole (fistula) in the roof of the mouth. In 36 patients, half received the standard two-layer repair, while the other half also had a small piece of fat from the cheek pla…
Matched conditions: CLEFT PALATE
Phase: NA • Sponsor: Tanta University • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New drug calms kids after cleft palate surgery
Symptom relief CompletedThis study tested whether a single dose of dexmedetomidine, given during surgery, can prevent severe agitation in children aged 1-7 after cleft palate repair. Sixty children were randomly assigned to receive either the drug or a placebo (saline). The main goal was to measure emer…
Matched conditions: CLEFT PALATE
Phase: PHASE3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Honey vs. antibiotic: which heals cleft palate surgery better?
Knowledge-focused CompletedThis study looked at whether a special honey (Trigona sp.) helps heal wounds after cleft palate surgery better than a standard antibiotic dressing. Twenty-four children aged 18 months to 6.5 years participated. Researchers measured a healing marker in saliva before and after surg…
Matched conditions: CLEFT PALATE
Phase: NA • Sponsor: Hasanuddin University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Cleft Surgery's hidden impact on palate blood flow revealed
Knowledge-focused CompletedThis study looked at how routine cleft repair surgery changes blood flow in the roof of the mouth. Researchers used a non-invasive probe to measure oxygen levels in the tissue before and after surgery in 77 patients. The goal was to understand the surgery's effect on tissue healt…
Matched conditions: CLEFT PALATE
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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French kids help set new standard for diagnosing speech disorders
Knowledge-focused CompletedThis study measured normal nasalance scores in 131 French-speaking children aged 8 to 10 using a non-invasive device called a Nasometer. The goal is to create reference values that help doctors diagnose velopharyngeal dysfunction, a common issue in children with cleft palate, wit…
Matched conditions: CLEFT PALATE
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC