CLEFT PALATE
Clinical trials for CLEFT PALATE explained in plain language.
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New expander shows promise for cleft patients
Disease control CompletedThis study tested a new device called the Leaf Self Expander in 20 children with cleft lip and palate to widen the upper jaw. The goal was to see if it works better than the standard expander by measuring bone and tooth changes with 3D scans. The children had already had lip and …
Matched conditions: CLEFT PALATE
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated May 17, 2026 13:59 UTC
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Fat graft patch shows promise for closing palate holes in cleft patients
Disease control CompletedThis study tested a new surgical method to repair a common complication after cleft palate surgery: a hole (fistula) in the roof of the mouth. 36 patients were split into two groups: one received standard two-layer closure, the other had an extra layer of fat graft placed between…
Matched conditions: CLEFT PALATE
Phase: NA • Sponsor: Tanta University • Aim: Disease control
Last updated May 11, 2026 20:51 UTC
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New study tests drug to calm kids after cleft palate surgery
Symptom relief CompletedThis study tested whether a single dose of dexmedetomidine, given during surgery, can prevent agitation in children aged 1-7 years after cleft palate repair. Sixty children were randomly assigned to receive either the drug or a placebo (saline). The main goal was to measure emerg…
Matched conditions: CLEFT PALATE
Phase: PHASE3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 14, 2026 12:05 UTC
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Cleft Surgery's hidden impact on palate blood flow revealed
Knowledge-focused CompletedThis study looked at how routine cleft repair surgery changes blood flow in the roof of the mouth. Researchers used a non-invasive probe to measure oxygen levels in the tissue before and after surgery in 77 patients. The goal was to understand how surgery affects healing and to p…
Matched conditions: CLEFT PALATE
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated May 17, 2026 13:53 UTC