CLEAR CELL RENAL CELL CARCINOMA
Clinical trials for CLEAR CELL RENAL CELL CARCINOMA explained in plain language.
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New hope for kidney cancer patients with bone metastases: drug combo trial launches
Disease control Not yet recruitingThis study tests a new drug called zanzalintinib, taken with a bone-strengthening agent, in 20 people whose kidney cancer has spread to the bones and has worsened after prior immunotherapy. The goal is to see if this combination can stop the cancer from growing for at least 12 mo…
Matched conditions: CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: Kelly Fitzgerald, MD • Aim: Disease control
Last updated May 16, 2026 23:46 UTC
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New Dual-Target CAR t therapy takes on Hard-to-Treat kidney cancer
Disease control Not yet recruitingThis early-phase study tests a new treatment called LNK001 for people with advanced or metastatic clear cell renal cell carcinoma (a type of kidney cancer) that has not responded to prior therapies. LNK001 is a type of immunotherapy where a patient's own immune cells are engineer…
Matched conditions: CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 16, 2026 23:38 UTC
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New drug combo aims to shrink kidney tumors before surgery
Disease control Not yet recruitingThis early-phase trial tests whether giving two immunotherapy drugs (botensilimab and balstilimab) before surgery is safe and helps shrink high-risk kidney cancers that haven't spread. About 16 adults with clear cell renal cell carcinoma will receive the drugs, then have their ki…
Matched conditions: CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 14, 2026 12:01 UTC
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Gut bacteria boost could help stop Cancer's return
Disease control Not yet recruitingThis study is testing if adding a specific probiotic (CBM588) to a standard immunotherapy drug (pembrolizumab) can better prevent kidney cancer from coming back after surgery. The trial will enroll 62 patients who have had surgery for high-risk kidney cancer. Researchers believe …
Matched conditions: CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Apr 09, 2026 19:33 UTC
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Urine test could spot kidney cancer types without a needle
Diagnosis Not yet recruitingThis study looks at tiny particles from tumors found in urine and blood to see if they can tell doctors what kind of kidney cancer a person has. Researchers will test stored urine samples from 300 people and also collect blood before and after kidney removal surgery. The goal is …
Matched conditions: CLEAR CELL RENAL CELL CARCINOMA
Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated May 16, 2026 23:51 UTC
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Scientists probe Bone's role in fighting spreading kidney cancer
Knowledge-focused Not yet recruitingThis is an early, small study to learn how a standard cancer drug (cabozantinib) changes the immune environment inside bones where kidney cancer has spread. Researchers will take small tissue samples (biopsies) from the bone before and after treatment to see what happens. The mai…
Matched conditions: CLEAR CELL RENAL CELL CARCINOMA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Apr 20, 2026 16:18 UTC