New immunotherapy combo aims to fight advanced kidney cancer

NCT ID NCT07159191

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a combination of two drugs—envafolimab (an immunotherapy injection) and axitinib (a targeted therapy pill)—as a first treatment for people with advanced kidney cancer that has spread or cannot be removed. About 30 participants will receive the treatment for up to 2 years. Researchers will measure how well the drugs shrink tumors and control the cancer, while closely monitoring side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Envafolimab (immunotherapy injection) and Axitinib (targeted therapy pill)

What this could lead to

If successful, this combination could offer a new first-line treatment option for advanced kidney cancer, potentially shrinking tumors and delaying disease progression.

What could go wrong

This is a small, early-phase (Phase 2) study with only 30 participants and no comparison group. The treatment may cause side effects like immune reactions or high blood pressure, and may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

clear cell renal carcinoma nonpapillary renal cell carcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••