CHRONIC LIMB-THREATENING ISCHEMIA
Clinical trials for CHRONIC LIMB-THREATENING ISCHEMIA explained in plain language.
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Spinning tool tested to save limbs from amputation
Disease control Not yet recruitingThis European study will test a procedure called orbital atherectomy in 250 patients with severe leg artery disease who are at risk of amputation. The procedure uses a tiny, spinning tool to gently scrape away hard calcium deposits from inside blocked leg arteries, aiming to open…
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Sponsor: Cardiovascular and Interventional Radiological Society of Europe • Aim: Disease control
Last updated Apr 02, 2026 06:56 UTC
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New blood flow technique aims to prevent leg amputations
Disease control Not yet recruitingThis study is testing a new approach called 'woundsome revascularization' to improve blood flow directly to foot wounds in patients with severe limb-threatening ischemia. Researchers want to see if this targeted approach helps prevent leg amputations and promotes wound healing be…
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New hope for saving limbs: testing a temporary artery scaffold
Disease control Not yet recruitingThis study is testing a new temporary scaffold device designed to help keep severely blocked leg arteries open after a procedure. It focuses on patients with diabetes or those on long-term dialysis who are at high risk of amputation. The goal is to see if using this device helps …
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Sponsor: Medical University of Graz • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Dissolving stents could save limbs from amputation
Disease control Not yet recruitingThis European study will test dissolving stents that release medication to keep leg arteries open in 400 patients with severe circulation problems that threaten limb loss. The temporary stents provide support while releasing drugs to prevent re-blockage, then naturally dissolve i…
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Sponsor: Cardiovascular and Interventional Radiological Society of Europe • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Could a popular diabetes drug target save limbs?
Knowledge-focused Not yet recruitingThis study aims to gather information to see if a future treatment for severe leg artery disease is possible. Researchers will compare blood samples from 50 patients with different stages of the disease to check for a specific protein target used by some diabetes drugs. The goal …
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC