CHRONIC LIMB-THREATENING ISCHEMIA
Clinical trials for CHRONIC LIMB-THREATENING ISCHEMIA explained in plain language.
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Could a common gout pill save legs and lives?
Disease control Not yet recruitingThis study tests whether a low-dose anti-inflammatory drug called colchicine can help people with severe leg artery disease (chronic limb-threatening ischemia) avoid amputation or death. About 200 adults who recently had a procedure to restore leg blood flow will take either colc…
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Phase: PHASE3 • Sponsor: Shin Kong Wu Ho-Su Memorial Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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New 'Woundsome' technique aims to save legs from amputation
Disease control Not yet recruitingThis study tests a procedure called woundsome revascularization in 50 people with chronic limb-threatening ischemia (CLTI), the most severe form of peripheral artery disease. Doctors use balloon angioplasty to open blocked arteries that supply blood directly to the wound area. Th…
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New study tests orbital atherectomy to save limbs in patients with severe leg artery disease
Disease control Not yet recruitingThis study will follow 250 people with chronic limb-threatening ischemia (CLTI) across Europe to see how well orbital atherectomy works in real life. The procedure uses a tiny spinning tool to gently remove hard calcium from leg arteries, making it easier for balloons or stents t…
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Sponsor: Cardiovascular and Interventional Radiological Society of Europe • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Dissolvable scaffolds could save legs from amputation in major new trial
Disease control Not yet recruitingThis Europe-wide study will follow 400 people with severe leg artery disease (chronic limb-threatening ischemia) to see if a new dissolvable, drug-coated scaffold can keep leg arteries open better than standard treatments. The scaffold releases medication to prevent re-blockage a…
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Sponsor: Cardiovascular and Interventional Radiological Society of Europe • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Could a diabetes drug help treat blocked leg arteries? new study investigates
Knowledge-focused Not yet recruitingThis observational study will examine whether a protein called the GLP-1 receptor is more active in patients with severe leg artery disease compared to those with milder symptoms. Researchers will take one extra blood sample from 50 adults with peripheral artery disease to measur…
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC