Dissolvable scaffolds could save legs from amputation in major new trial

NCT ID NCT07270575

First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 3 times

Summary

This Europe-wide study will follow 400 people with severe leg artery disease (chronic limb-threatening ischemia) to see if a new dissolvable, drug-coated scaffold can keep leg arteries open better than standard treatments. The scaffold releases medication to prevent re-blockage and then dissolves over time, avoiding the long-term risks of permanent metal stents. Participants must have heavily calcified arteries in the lower leg and be willing to undergo the procedure.

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Conditions

The condition(s) this trial relates to.

Chronic Limb-Threatening Ischemia limb ischemia peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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