CHRONIC LIMB-THREATENING ISCHEMIA
Clinical trials for CHRONIC LIMB-THREATENING ISCHEMIA explained in plain language.
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New Bone-Moving surgery could help avoid amputation in 'No Option' patients
Disease control TerminatedThis study was designed to test a new surgical technique called transverse tibial bone transport in people with chronic limb-threatening ischemia (CLTI) who have no standard treatment options left. The procedure involves slowly moving a small piece of shinbone to stimulate new bl…
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Phase: NA • Sponsor: University Hospitals Cleveland Medical Center • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Dissolvable scaffold for leg arteries under Real-World watch
Disease control OngoingThis study follows about 200 people with chronic limb-threatening ischemia (CLTI) who receive the Esprit BTK System, a dissolvable scaffold coated with a drug to keep leg arteries open. The goal is to see how safe and effective it is in routine medical practice. Researchers will …
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New catheter aims to save limbs when all else fails
Disease control ENROLLING_BY_INVITATIONThis study tests a device called the Boomerang Catheter in 120 people with chronic limb-threatening ischemia (CLTI), a severe condition where blocked leg arteries can lead to amputation. The catheter creates a connection between a vein and an artery to reroute blood around the bl…
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Phase: NA • Sponsor: Aveera Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New balloon could save legs from amputation in PAD patients
Disease control OngoingThis study compares a special balloon coated with sirolimus (a drug that prevents re-blockage) to a standard balloon for opening blocked arteries below the knee in people with peripheral artery disease. About 230 participants will be randomly assigned to one of the two treatments…
Matched conditions: CHRONIC LIMB-THREATENING ISCHEMIA
Phase: NA • Sponsor: Jena University Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC