New Bone-Moving surgery could help avoid amputation in 'No Option' patients

NCT ID NCT07175129

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study was designed to test a new surgical technique called transverse tibial bone transport in people with chronic limb-threatening ischemia (CLTI) who have no standard treatment options left. The procedure involves slowly moving a small piece of shinbone to stimulate new blood vessel growth and help heal wounds. The goal was to see if it could prevent major amputation and improve blood flow, but the study was withdrawn before any patients were enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Transverse Tibial Bone Transport procedure

What this could lead to

If it works, this could offer a way to save the leg and avoid amputation for people with severe circulation problems who have run out of standard treatments.

What could go wrong

This is a very early pilot study that was withdrawn before enrolling anyone, so we have no results yet. The procedure is new and unproven, and there may be risks like infection or bone healing problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Chronic Limb-Threatening Ischemia Diabetic Foot limb ischemia peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States