New dissolvable scaffold tested for saving legs from severe artery disease

NCT ID NCT06656364

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 21 times

Summary

This study looks at a device called Esprit BTK, a scaffold that slowly dissolves, used to open blocked leg arteries in people with chronic limb-threatening ischemia (CLTI), a serious condition that can lead to amputation. About 200 participants will be followed to see if the device keeps arteries open safely without major complications like limb loss or death. The goal is to confirm the device works well in everyday medical practice.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Al Qassimi Hospital

    Sharjah city, Emirate of Sharjah, 3500, United Arab Emirates

  • Ansaarie Cardiac and Endovascular Center of Excellence

    Saint Augustine, Florida, 32080, United States

  • Ascension St. John Jane Phillips

    Bartlesville, Oklahoma, 74006, United States

  • Auckland City Hospital

    Auckland, 1003, New Zealand

  • Baylor All Saints Medical Center at Fort Worth

    Fort Worth, Texas, 76104, United States

  • Cardiovascular Consultants of South Georgia, LLC

    Thomasville, Georgia, 31792, United States

  • Carolinas Medical Center

    Charlotte, North Carolina, 28203, United States

  • Charlton Memorial Hospital

    Fall River, Massachusetts, 02720, United States

  • Christ Hospital

    Cincinnati, Ohio, 45255, United States

  • ClinRé 001-100 - Denver

    Denver, Colorado, 80220, United States

  • Erlanger Medical Center

    Chattanooga, Tennessee, 37403, United States

  • First Coast Cardiovascular Institute

    Jacksonville, Florida, 32256, United States

  • Good Samaritan Hospital

    Los Angeles, California, 90017, United States

  • Grady Clinical Research Center

    Atlanta, Georgia, 30303, United States

  • HCA Houston Healthcare Medical Center

    Houston, Texas, 77004, United States

  • Hendrick Medical Center

    Abilene, Texas, 79601, United States

  • Hightower Clinical

    Oklahoma City, Oklahoma, 73102, United States

  • HonorHealth

    Scottsdale, Arizona, 85258, United States

  • Jackson Heart Clinic

    Jackson, Mississippi, 39216, United States

  • Johnson City Medical Center Hospital

    Johnson City, Tennessee, 37604, United States

  • Medical City Arlington

    Arlington, Texas, 76014, United States

  • Mount Sinai Hospital

    New York, New York, 10019, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • New York Presbyterian Hospital-Cornell University

    New York, New York, 10021, United States

  • New York University Hospital

    New York, New York, 10016, United States

  • New York-Presbyterian/Columbia University Medical Center

    New York, New York, 10032, United States

  • North Mississippi Medical Center

    Tupelo, Mississippi, 38801, United States

  • Oklahoma Heart Hospital

    Oklahoma City, Oklahoma, 73120, United States

  • Pima Heart and Vascular Clinical Research

    Tucson, Arizona, 85718, United States

  • Queen Mary Hospital

    Hong Kong, HK SAR, 999077, Hong Kong

  • SIU School of Medicine

    Springfield, Illinois, 62794, United States

  • Sorin Medical

    New York, New York, 10005, United States

  • St. Francis Hospital

    Roslyn, New York, 11576, United States

  • St. Vincent Hospital

    Indianapolis, Indiana, 46260, United States

  • Staten Island University Hospital - North

    Staten Island, New York, 10305, United States

  • Tallahassee Research Institute

    Tallahassee, Florida, 32308, United States

  • UCSF Fresno

    Fresno, California, 93720, United States

  • University of Texas Southwestern Medical Center at Dallas

    Dallas, Texas, 75390, United States

  • Washington Hospital Center

    Washington D.C., District of Columbia, 20010, United States

Conditions

Explore the condition pages connected to this study.