CHRONIC KIDNEY DISEASE, STAGE 5

This early-stage trial tests a vaccine called OSU-2131, designed to help the immune system fight Epstein-Barr virus (EBV). EBV can cause cancers in people who have weakened immune systems, such as those awaiting organ transplants. The study includes healthy volunteers and transpl…

This study tests a treatment called physiologic insulin resensitization (PIR) in 120 adults with advanced chronic kidney disease and type 2 diabetes. The goal is to see if PIR can improve kidney function better than standard care. Participants will be randomly assigned to receive…

This trial tests whether a daily capsule containing probiotics and prebiotics can lower inflammation and improve nutrition in adults with chronic kidney disease who are on peritoneal dialysis. Participants take either the synbiotic or a placebo for six months, with blood tests an…

This study tests a home monitoring system called VIEWER for people with advanced chronic kidney disease (stage 5) or end-stage renal disease. The system includes a tablet, blood pressure cuff, scale, oxygen monitor, and motion tracker. Researchers want to see if using this platfo…

This study tests whether a ketoanalogue supplement (Ketosteril) can prevent muscle loss in 100 adults with stage 4 or 5 chronic kidney disease who are on a moderately low-protein diet. Participants take the supplement daily for a period, and researchers measure changes in muscle …

This study tests whether a 12-week home-based exercise program is safe and practical for adults aged 60 and older who are waiting for a kidney transplant. Participants will either receive usual care plus a physical activity tracker, or usual care plus the tracker and online exerc…

This small pilot study tests a simple tool called CKD Topics that helps people with advanced chronic kidney disease (stages 4-5) set the agenda for their doctor visits. The study includes 30 patients, their care partners, and clinic staff from rural areas. The goal is to see if t…

This study aims to understand the link between calcium and phosphorus from food and the stage of kidney disease in patients with advanced chronic kidney disease (stage 4-5). Researchers will compare two methods of tracking diet: taking photos of meals and weighing food. The goal …

This study is testing a new food questionnaire called EvalSel to see how well it measures salt intake in hospitalized patients with high blood pressure or kidney problems. Researchers will compare the questionnaire results with a 24-hour urine test, which is the gold standard for…

This study follows 544 adults with advanced kidney disease who need an arteriovenous fistula for dialysis. Researchers want to find out why some people develop hand ischemia (reduced blood flow) after surgery. They will track symptoms like cold hands, pain, or sores to identify r…

This study tests whether a digital website called Careverse can help caregivers of people with serious illnesses engage more in advance care planning. About 200 caregivers will be randomly assigned to use the website or receive usual care. Researchers will measure how involved ca…