Muscle-Saving supplement tested in kidney patients

NCT ID NCT07374042

Recruiting now Disease control Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a ketoanalogue supplement (Ketosteril) can prevent muscle loss in 100 adults with stage 4 or 5 chronic kidney disease who are on a moderately low-protein diet. Participants take the supplement daily for a period, and researchers measure changes in muscle mass using DEXA scans. The goal is to find a way to help patients maintain strength and delay the need for dialysis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: keto acid analog (Ketosteril)
What this could lead to: If it works, this could offer a way to protect muscle mass in people with advanced kidney disease, potentially delaying the need for dialysis.
What could go wrong: This is a phase 3 trial, but it's still relatively small (100 participants) and focuses on a specific patient group. The supplement may not prevent muscle loss, and some people may find the diet hard to follow.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KIDNEY DISEASE, CHRONIC

Contacts and locations

Locations

CHU de Clermont-Ferrand
RECRUITING

Clermont-Ferrand, 63000, France

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