CHRONIC INSOMNIA

This pilot study is testing a device that sends a mild electrical current to the brain (tACS) to see if it can reduce anxiety and improve sleep in people with generalized anxiety disorder and chronic insomnia. Thirty adults will receive 20 sessions over four weeks. The goal is to…

This study compares the effectiveness, safety, and long-term benefits of commonly used insomnia medications, including prescription drugs like zolpidem and trazodone, and over-the-counter options like melatonin and diphenhydramine. Researchers will enroll 1,200 adults with chroni…

This study looks at how to best offer cognitive behavioral therapy for chronic insomnia to older veterans at 20 VA clinics. About 20 veterans will take part to see if the therapy helps them sleep better and feel better. The goal is to find the best way to bring this effective tre…

This study compares two behavioral programs for people with chronic pain, chronic insomnia, and long-term opioid use. One program uses cognitive behavioral therapy for insomnia (CBT-I), the other is standard treatment. The goal is to see if improving sleep can also reduce opioid …

This study tests a brief group therapy called Acceptance and Commitment Therapy for insomnia (ACT-i) in 76 adults aged 18-59 with chronic insomnia and mild depression or anxiety. Participants are randomly assigned to either ACT-i or a general support group. The goal is to see if …

This study tests a type of hypnotherapy called E2R for people with chronic insomnia. It compares E2R to usual care (like sleep medications) to see if it reduces insomnia severity. About 136 adults with chronic insomnia will take part, and the goal is to find a safer, non-drug opt…

This study looks at whether adding yoga to usual care can reduce insomnia severity in adults aged 18-65 with chronic insomnia. 72 participants will be split into three groups: yoga plus standard care, stretching plus standard care, or standard care alone. The main goal is to see …

This study tests whether wearing a vibrating device on the forehead for 15 minutes before bed can improve sleep and memory in people with chronic insomnia. 120 adults aged 18-65 with trouble falling asleep will use either the active device or a sham version for 4 weeks. Participa…

This study looks at how Cognitive Behavioral Therapy for Insomnia (CBT-I) affects the body's stress system, including the hormone cortisol. Researchers will track 115 adults with chronic insomnia, measuring sleep and stress markers before, during, and after therapy. The goal is t…

This study compares how people with chronic insomnia and healthy controls recognize facial emotions. Using eye-tracking, researchers will look for subtle differences in attention and emotional processing. The goal is to better understand social challenges linked to insomnia and i…

This study looks at how chronic sleep problems and pain sensitivity are connected in people with long-term low back pain and insomnia. Researchers will use brain imaging, pain tests, and blood/stool samples in 80 adults to understand the underlying brain mechanisms. The goal is t…