Can talk therapy for sleep tame your stress hormones?

NCT ID NCT07156383

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how Cognitive Behavioral Therapy for Insomnia (CBT-I) affects the body's stress system, including the hormone cortisol. Researchers will track 115 adults with chronic insomnia, measuring sleep and stress markers before, during, and after therapy. The goal is to understand why CBT-I works and whether it helps people with short sleep more than those who sleep longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cognitive Behavioral Therapy for Insomnia (CBT-I)

What this could lead to

If successful, this could clarify how CBT-I works on a biological level, potentially leading to more targeted insomnia treatments.

What could go wrong

This is an early-stage mechanistic study, not a treatment trial. It may not produce clear results, and findings may not apply to all insomnia patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

insomnia Sleep Deprivation sleep-wake disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Notre Dame

    RECRUITING

    Notre Dame, Indiana, 46556, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact