CERVICAL CARCINOMA

This study looks at whether surgically removing lymph nodes near the aorta before standard chemoradiation helps people with stage IIIC1 cervical cancer live longer without the disease coming back. About 510 participants will be randomly assigned to either standard treatment or st…

This study compares HPV testing on self-collected vaginal samples versus samples collected by a doctor during a pelvic exam. About 500 women referred for colposcopy or cervical procedures will participate. The goal is to see if self-collection is accurate enough to increase scree…

This study compares two types of radiation therapy—proton therapy and standard IMRT—given after surgery for endometrial or cervical cancer. The goal is to see which one causes fewer bowel and bladder side effects. About 120 people who have had a hysterectomy for these cancers wil…

This study compares giving cancer treatment at home versus in a clinic for 27 adults with various cancers in the Florida Panhandle. The goal is to see if patients prefer home care and if it is safe. Participants will receive their usual cancer drugs either at home or in the clini…

This study tests whether a vaginal cream containing the hormone DHEA can improve vaginal health in women who had radiation for gynecologic, anal, or rectal cancer. Radiation often causes dryness, burning, and pain. The trial will enroll 25 women to see if the cream is safe and to…

This study looks at how pelvic radiation therapy for cervical cancer changes the body's immune response, both in the tumor and throughout the body. Researchers will collect blood and tumor samples from 110 patients before, during, and after treatment to understand these effects. …

This study tests a community program to increase cancer screening rates among low-income women in Ohio. The program includes patient education, media campaigns, and training health workers. Researchers will compare screening rates before and after the program to see if it helps m…