Could a simple Self-Swap replace the speculum for cervical cancer screening?
NCT ID NCT07281430
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether self-collected vaginal samples for HPV testing work as well as samples collected by a doctor during a pelvic exam. The goal is to make cervical cancer screening more accessible and comfortable. About 500 people referred for colposcopy or cervical procedures will provide both a self-collected sample and a clinician-collected sample, and researchers will compare the accuracy of the HPV test results.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HPV self-collection test
What this could lead to
If successful, this could make cervical cancer screening easier and more accessible by allowing people to collect their own samples at home.
What could go wrong
This is an early-stage study focused on accuracy, not on preventing cancer directly. The self-collection method may not be as reliable as clinician-collected samples.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Emory University Hospital/Winship Cancer Institute
RECRUITINGAtlanta, Georgia, 30322, United States
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Huntsman Cancer Institute/University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
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Louisiana State University
RECRUITINGLafayette, Louisiana, 70503, United States
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Louisiana State University Health Science Center
RECRUITINGNew Orleans, Louisiana, 70112, United States
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Minneapolis VA Medical Center
RECRUITINGMinneapolis, Minnesota, 55417, United States
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Montefiore Medical Center-Einstein Campus
RECRUITINGThe Bronx, New York, 10461, United States
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Montefiore Medical Center-Weiler Hospital
RECRUITINGThe Bronx, New York, 10461, United States
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UNC Lineberger Comprehensive Cancer Center
RECRUITINGChapel Hill, North Carolina, 27599, United States
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UPMC-Magee Womens Hospital
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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UT MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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University of Alabama at Birmingham Cancer Center
RECRUITINGBirmingham, Alabama, 35233, United States
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University of Cincinnati Cancer Center-UC Medical Center
RECRUITINGCincinnati, Ohio, 45219, United States
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University of New Mexico Cancer Center
RECRUITINGAlbuquerque, New Mexico, 87106, United States
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University of Oklahoma
RECRUITINGOklahoma City, Oklahoma, 73190, United States
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University of Oklahoma Health Sciences Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
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University of Pennsylvania/Abramson Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of Pittsburgh Cancer Institute (UPCI)
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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West Virginia University Healthcare
RECRUITINGMorgantown, West Virginia, 26506, United States
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