CACHEXIA
Clinical trials for CACHEXIA explained in plain language.
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New drug aims to stop wasting in cancer patients
Symptom relief Recruiting nowThis early-stage study tests a drug called AV-380 in 30 adults with advanced cancer who are losing weight (cachexia). The drug targets a protein linked to weight loss. Researchers will check safety and how the drug works in the body when given with standard chemotherapy.
Matched conditions: CACHEXIA
Phase: PHASE1 • Sponsor: AVEO Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated May 17, 2026 05:08 UTC
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New pill may help cervical cancer patients keep weight and strength during chemo
Symptom relief Recruiting nowThis study tests a new, easier-to-absorb form of megestrol acetate (a drug that boosts appetite) in 88 women with advanced cervical cancer who are undergoing chemoradiotherapy. The goal is to see if it helps prevent weight loss and muscle wasting, which are common and dangerous s…
Matched conditions: CACHEXIA
Phase: PHASE1 • Sponsor: Second Xiangya Hospital of Central South University • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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New drug aims to fight deadly wasting in pancreatic cancer patients
Symptom relief Recruiting nowThis study tests if adding ponsegromab to standard chemotherapy can help adults with advanced pancreatic cancer who are losing weight and have poor appetite (cachexia). About 982 participants will receive either ponsegromab or a placebo alongside their first chemo treatment. The …
Matched conditions: CACHEXIA
Phase: PHASE2, PHASE3 • Sponsor: Pfizer • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Genetic clues to muscle wasting in pancreatic cancer could lead to new treatments
Knowledge-focused Recruiting nowThis study looks at how a person's genes might affect their risk of developing cancer cachexia, a severe muscle wasting condition common in pancreatic cancer. Researchers will collect blood samples from 100 adults with pancreatic cancer to find genetic markers linked to weight lo…
Matched conditions: CACHEXIA
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated May 17, 2026 05:08 UTC
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Behind the scenes: scientists Double-Check lab tests for better research
Knowledge-focused Recruiting nowThis study aims to validate and check the reproducibility of laboratory tests, equipment, and techniques used in research on chronic diseases like obesity, diabetes, and heart disease. Researchers will compare old and new testing methods to ensure results are accurate and consist…
Matched conditions: CACHEXIA
Sponsor: Bettina Mittendorfer • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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New study aims to unravel the mystery of Cancer-Related muscle wasting
Knowledge-focused Recruiting nowThis study is for people with stomach, pancreas, or bowel cancer who are having surgery, as well as some people without cancer for comparison. The goal is to understand why some patients lose muscle and weight (cachexia) and how it affects their recovery. Researchers will track c…
Matched conditions: CACHEXIA
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC