New DNA drug targets advanced cancer and wasting

NCT ID NCT06736275

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests a new drug called SXRN, made from DNA, in 28 people with advanced solid tumors who have run out of standard options. The main goals are to check safety and find the right dose, while also seeing if it helps with appetite and physical function. The study compares SXRN to a placebo over 14 days of IV infusions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SXRN plasmid DNA

What this could lead to

If it works, this could point toward a new way to control tumor growth and improve appetite and physical function in people with advanced cancer.

What could go wrong

This is a very early (Phase 1) trial with only 28 people, so safety and dosing are still being figured out. It may not shrink tumors or improve symptoms, and side effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cachexia cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Hospital Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, 100021, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••