BREAST NEOPLASMS

This study tests a new drug, imlunestrant, in 600 premenopausal women with estrogen receptor-positive, HER2-negative breast cancer. It compares how the drug affects tumor cells and ovaries versus tamoxifen, with or without ovarian suppression. The goal is to find a better treatme…

This study is a post-marketing surveillance required by Korean regulators to monitor Talzenna's safety and effectiveness in real-world clinical practice. It will enroll 600 patients with advanced breast cancer and a BRCA gene mutation who are already scheduled to receive Talzenna…

This study looks at 40 adults with a common type of advanced breast cancer (HR+/HER2-) that has stopped responding to standard hormone therapy. Researchers want to find the best order to give two targeted drugs (called antibody-drug conjugates) to control the cancer longer and im…

This study aims to see how well an ultrasound-guided needle biopsy can detect breast cancer that has spread to the lymph nodes under the arm. Researchers will enroll 200 adults with newly diagnosed breast cancer. They will use ultrasound to find suspicious lymph nodes and then ta…

This study will test if artificial intelligence can create clear breast MRI images without using contrast dye. Researchers will use a special type of MRI scan (diffusion-weighted imaging) to generate synthetic images that might help diagnose breast cancer. If successful, this cou…

This study is testing a new smartphone app designed to help breast cancer patients manage symptoms during chemotherapy. The app asks patients to report their symptoms and then gives personalized advice based on medical guidelines. Nurses can also use the app to make better care d…

This study looks at whether using a special skin substitute called SureDerm during breast-conserving surgery helps women feel better about how their breasts look afterward. About 116 women with breast cancer will be randomly assigned to get either standard surgery or surgery with…

This study tests a program called AIMSS-CARE for breast cancer patients in Ethiopia who have joint and muscle pain from hormone therapy. The program includes exercise, education, symptom tracking, and follow-up. 88 patients will be randomly assigned to the program or usual care t…

This study looks at how to best help people who finished early-stage breast cancer treatment return to work, social life, and daily activities. About 352 participants will try different combinations of three support tools: identifying priorities, education, and guided goal-settin…

This study tests whether listening to positive self-affirmation audio recordings can help reduce pain, depression, anxiety, and stress in women who have had a mastectomy. Forty-two women will be randomly assigned to either listen to the affirmations or receive standard care. The …

This study aims to find the best way to encourage people to get recommended health screenings for cancer and chronic diseases like diabetes. Over 235,000 participants in Chile will receive different types of messages via WhatsApp, some focusing on risk, others on peace of mind, a…

This study tests whether a special training program can help women with visual impairments get screened for breast and cervical cancer. About 74 women over age 40 will receive education on cancer risks and how to book screenings. Researchers will check if more women get screened …