BRCA1 MUTATION

This study is testing a new method to screen for breast cancer using a simple blood test analyzed by a special laser. Researchers are comparing results from this 'liquid biopsy' to standard mammograms in 1,100 women, including those with breast cancer, those without, and those wi…

This study is testing a specific, less invasive surgery for women with BRCA gene mutations who are at high risk for ovarian cancer. The surgery removes the ends of the fallopian tubes, where this cancer often starts, while leaving the ovaries intact to preserve natural hormone pr…

This study aims to discover which inherited gene mutations might increase a person's risk of developing lobular breast cancer. Researchers will analyze blood samples from 800 patients already diagnosed with this specific type of breast cancer. The goal is to identify new genetic …

This study aims to understand how BRCA1 or BRCA2 gene mutations affect the immune system's response to the seasonal flu vaccine. Researchers are enrolling 50 healthy adults with these mutations but no cancer history to measure their antibody levels before and after vaccination. T…

This study is testing a new, easier way to help family members of people with a BRCA gene mutation learn about genetic testing. It compares a web-based education program followed by a short phone call to the usual way information is shared. The goal is to see if this approach hel…

This study aims to learn how to offer BRCA gene testing to a larger number of people and make it a regular part of healthcare. It involves over 5,400 adults of Ashkenazi Jewish ancestry who have not had this genetic test before. The research focuses on how people decide to get te…