BRCA gene Carriers' immune system put to the test with flu shot

NCT ID NCT04499534

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 33 times

Summary

This study checks how well the immune system works in healthy people with BRCA1 or BRCA2 gene mutations. About 50 adults over age 25 who carry these gene changes but have not had cancer will get a seasonal flu vaccine. Researchers will measure their antibody and immune cell responses to see if the mutation affects overall immune fitness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.