BRAIN TUMOR ADULT

This early-phase study tests a personalized cell therapy called B7-H3 CAR T cells in 70 children and young adults whose brain tumors have come back or are growing despite standard treatment. The therapy uses the patient's own immune cells, modified to recognize and attack a prote…

This study tests a stepped-care program to support relatives of people with serious brain injuries or tumors. The program offers information, screening, and extra help based on each caregiver's needs. 160 relatives will either receive this support or usual care. The goal is to re…

This study looks at whether a 3-month supervised exercise program is doable for adults with brain tumors. Researchers will track how many patients join and stick with the program, and measure its effects on quality of life, anxiety, depression, and cancer symptoms. The goal is to…

This study tests a special 3D viewer (Mixed Reality) to help surgeons plan where to cut during brain tumor removal. About 54 adults will take part. The goal is to see if the viewer makes planning more accurate and faster than current methods.

This study tests a new AI tool that helps surgeons spot brain tumors during surgery using ultrasound. The tool creates a real-time outline of the tumor, which may help remove more of it safely. About 100 adults having brain tumor surgery will take part. The goal is to see if the …

This study tests whether a computer can decode what a person is saying from brain signals recorded during awake brain tumor surgery. Twenty adults with brain tumors near language areas will name pictures while electrodes on the brain's surface capture their neural activity. The g…

This study tests whether special MRI scans can spot areas where brain tumors have spread into surrounding tissue, which standard scans miss. About 20 adults with suspected high-grade glioma will get advanced imaging before surgery. The goal is to create a map of tumor infiltratio…

This study looks at how standard brain radiation therapy affects thinking and memory in 40 adults with brain tumors (primary or metastatic). Researchers will measure specific proteins in the blood and use brain scans to understand the biological changes behind cognitive decline. …

This study explores whether physical therapy, alone or combined with brain stimulation, can help the brain reorganize before surgery in adults with high-grade glioma near movement areas. About 63 participants will be randomly assigned to standard care, physical therapy, or physic…