BRAIN TUMOR ADULT

This study tests whether adding the chemotherapy drug capecitabine to the standard temozolomide regimen can help people with newly diagnosed glioblastoma live longer without their tumor growing. About 67 adults who have completed initial radiation and chemo will take both pills a…

This study looks at a special type of stitch (STRATAFIX) already approved by the FDA for closing wounds after brain or spine surgery. Researchers want to see if it helps wounds heal better and with fewer problems. About 160 adults having brain or spine surgery will take part. The…

This early study tests a special helmet that uses focused ultrasound to temporarily open the blood-brain barrier in people with glioblastoma. The goal is to let more chemotherapy reach the tumor. Ten adults who have already had surgery and standard chemo will receive the ultrasou…

This study is building a large database of MRI scans from 3000 adults with malignant brain tumors (gliomas, metastases, lymphomas). Researchers will train an artificial intelligence system to automatically identify and classify these tumors. The goal is to improve non-invasive di…

This study tests whether a 12-week tele-exercise program called RISE-YA can help reduce cancer-related fatigue in young adults (ages 18-39) who are brain tumor survivors. Participants receive energy conservation counseling, behavior coaching, and exercise training via video calls…

This study looks at whether training paramedics with simulations can make brain tumor patients more satisfied with their care. About 250 adults with a newly discovered brain tumor will fill out a questionnaire after their hospital stay. The goal is to see if this training helps p…

This study watches 200 adults having brain tumor surgery to see how often cerebrospinal fluid leaks happen and what makes them more likely. The goal is to find ways to prevent leaks and help people recover faster. No new treatment is being tested—just careful observation.

This study compares two common methods of closing the skin after brain tumor surgery: a continuous stitch under the skin using absorbable thread versus separate stitches through the skin using non-absorbable thread. Researchers want to see which method leads to fewer wound proble…

This observational study uses a special MRI technique with hyperpolarized carbon-13 pyruvate to see how brain tumors use energy. Researchers will measure metabolic byproducts in 25 adults with brain tumors before any treatment. The goal is to learn more about tumor metabolism, no…

This study investigates whether brain surface recordings can decode Mandarin Chinese speech, including tones, from imagined speech. About 50 participants with brain tumors or epilepsy will have temporary electrodes placed during surgery, and 10 people with severe speech loss will…