Brain recordings during awake surgery aim to read patients' thoughts

NCT ID NCT07499479

Not yet recruiting Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether speech can be decoded from brain activity recorded during awake brain tumor surgery. Twenty adult patients will have a special graphene electrode grid placed on their brain surface for up to two hours while they name pictures. Researchers will use machine learning to see if they can predict which picture the patient named from the brain signals alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: INBRAIN Graphene Cortical Interface (high-density graphene ECoG grid)
What this could lead to: If successful, this could lead to better ways to map language areas during brain surgery, potentially improving surgical outcomes.
What could go wrong: This is a very early, small study (20 participants) focused on recording, not treatment. The decoding may not work as hoped, and results may not apply to other patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain cancer brain neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN TUMOR ADULT

Contacts and locations

Locations

Department of neurosurgery Lariboisière hospital-APHP

Paris, Île-de-France Region, 75010, France

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