BRAIN METASTASES
Clinical trials for BRAIN METASTASES explained in plain language.
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New combo tackles brain tumors in melanoma and kidney cancer patients
Disease control TerminatedThis study tested a combination of two drugs, pembrolizumab and lenvatinib, in 18 adults with melanoma or kidney cancer that had spread to the brain. Participants had already received anti-PD-1/PD-L1 therapy. The goal was to see if the drug combo could shrink or eliminate brain t…
Matched conditions: BRAIN METASTASES
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Promising combo for brain metastases hits early snag: trial ends after just one patient
Disease control TerminatedThis early-stage trial aimed to see if combining three drugs (tucatinib, trastuzumab, and capecitabine) with precise radiation (SRS) is safe for people with HER2-positive breast cancer that has spread to the brain. Only one person enrolled before the study was terminated, so we h…
Matched conditions: BRAIN METASTASES
Phase: PHASE1 • Sponsor: Baptist Health South Florida • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Brain tumor radiation study halted early – what it means for patients
Knowledge-focused TerminatedThis study aimed to track quality of life in 52 patients with brain metastases who received radiosurgery (Gamma Knife). Patients filled out questionnaires before treatment and every 3 months for a year. The study was terminated early, so the full impact on daily life remains uncl…
Matched conditions: BRAIN METASTASES
Phase: NA • Sponsor: Centre Oscar Lambret • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC