BORDERLINE PERSONALITY DISORDER (BPD)
Clinical trials for BORDERLINE PERSONALITY DISORDER (BPD) explained in plain language.
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Could ketamine ease severe BPD symptoms? new pilot study aims to find out
Symptom relief Not yet recruitingThis pilot study will test whether two intravenous infusions of ketamine, given 24 hours apart, can quickly reduce symptoms in 38 adults with severe borderline personality disorder (BPD). Participants also receive standard psychiatric care. The main goal is to see if symptoms imp…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: PHASE2 • Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Can writing about trauma in a group ease PTSD for those with BPD traits?
Symptom relief Not yet recruitingThis study tests whether a 10-week virtual group therapy, where people write about their traumatic experiences, can reduce PTSD symptoms in adults who also have borderline personality disorder (BPD) traits. The therapy is called Group Extended Written Exposure Therapy (GE-WET). R…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: St. Joseph's Healthcare Hamilton • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Can ketamine plus therapy curb suicidal thoughts? new trial aims to find out.
Symptom relief Not yet recruitingThis study tests whether combining ketamine infusions with dialectical behavioural therapy (DBT) can reduce suicidal thoughts more effectively than a placebo plus DBT. About 120 adults with borderline personality disorder and treatment-resistant depression or bipolar disorder wil…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: PHASE2 • Sponsor: Joshua Rosenblat • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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New therapy aims to ease double mental health burden
Symptom relief Not yet recruitingThis study compares a new trauma-focused therapy (MBT-TF) with standard therapy for adults who have both borderline personality disorder and complex PTSD. The goal is to see if the new approach is practical and helpful for reducing symptoms. Forty participants will be followed fo…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: Eva Rüfenacht • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Could a Culturally-Tuned therapy ease emotional turmoil in underserved regions?
Symptom relief Not yet recruitingThis study tests whether a version of dialectical behavior therapy (DBT) that has been adapted to fit local cultures can help adults aged 18-45 with borderline personality disorder better manage their emotions and reduce self-harm. The therapy is being studied in a low- and middl…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: Pakistan Association of Cognitive Therapists • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Rewriting your past to build a better future: new trial for BPD
Symptom relief Not yet recruitingThis study tests whether autobiographical rewriting workshops, added to standard therapy, can help people with borderline personality disorder (BPD) function better socially and at work. 140 participants will either take part in these workshops or do non-specific writing sessions…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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New study links menstrual cycle to emotional struggles in autistic women
Knowledge-focused Not yet recruitingThis study looks at how emotional regulation varies across the menstrual cycle in autistic women. Researchers will compare them to women with borderline personality disorder, premenstrual dysphoric disorder, and those without any diagnosed condition. The goal is to better underst…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Brain scans reveal why social rejection hurts more in BPD
Knowledge-focused Not yet recruitingThis study uses EEG brain scans to understand how people with borderline personality disorder (BPD) process social rejection. Researchers will measure brain activity while participants play a virtual ball-tossing game designed to make them feel left out. The goal is to identify d…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: Hôpital le Vinatier • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC