BORDERLINE PERSONALITY DISORDER (BPD)
Clinical trials for BORDERLINE PERSONALITY DISORDER (BPD) explained in plain language.
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Could a single day of brain zaps curb suicidal urges in BPD?
Symptom relief Not yet recruitingThis study tests a new one-day treatment for adults with borderline personality disorder who have serious suicidal thoughts. It combines a medication (D-cycloserine) with up to 20 short sessions of transcranial magnetic stimulation (TMS) over about 12 hours. The goal is to see if…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: PHASE1, PHASE2 • Sponsor: Mclean Hospital • Aim: Symptom relief
Last updated May 17, 2026 08:54 UTC
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Could ketamine and therapy curb suicidal thoughts in Tough-to-Treat patients?
Symptom relief Not yet recruitingThis study looks at whether a drug called ketamine, given through an IV, along with a type of talk therapy (DBT), can help reduce suicidal thoughts in people with borderline personality disorder and depression or bipolar disorder. About 120 adults will get either ketamine or a pl…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: PHASE2 • Sponsor: Joshua Rosenblat • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Writing away trauma: new group therapy aims to ease PTSD in complex cases
Symptom relief Not yet recruitingThis study tests whether a 10-week virtual group writing therapy can reduce PTSD symptoms in adults who also have borderline personality disorder or its traits. Participants write about their trauma using specific instructions during weekly 2-hour online sessions. The goal is to …
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: St. Joseph's Healthcare Hamilton • Aim: Symptom relief
Last updated May 13, 2026 16:01 UTC
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Ketamine infusions aim to ease severe BPD symptoms in new pilot study
Symptom relief Not yet recruitingThis pilot study tests whether two low-dose ketamine infusions, given 24 hours apart, can quickly reduce symptoms in people with severe borderline personality disorder (BPD). About 38 adults will receive the infusions along with standard psychiatric care and be followed for up to…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: PHASE2 • Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated May 13, 2026 16:00 UTC
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Rewriting your past to fix your future: new hope for BPD?
Symptom relief Not yet recruitingThis study tests whether special writing workshops, added to standard talk therapy, can help people with borderline personality disorder (BPD) improve their social and work lives. About 140 adults aged 18–45 with BPD will take part. One group will rewrite their personal memories …
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Symptom relief
Last updated May 11, 2026 20:52 UTC
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Can a Culturally-Tailored therapy ease emotional pain in developing nations?
Symptom relief Not yet recruitingThis study tests a version of dialectical behavior therapy (DBT) that has been adapted to fit local cultures in low- and middle-income countries. The goal is to help 220 adults with borderline personality disorder better manage their emotions and reduce self-harm or suicidal beha…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: Pakistan Association of Cognitive Therapists • Aim: Symptom relief
Last updated May 07, 2026 18:42 UTC
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New therapy aims to ease trauma and borderline symptoms
Symptom relief Not yet recruitingThis study compares a new trauma-focused version of mentalization-based treatment (MBT-TF) with standard MBT for adults who have both borderline personality disorder and complex PTSD. The goal is to see if the new therapy is practical and acceptable to patients and clinicians. Ab…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: Eva Rüfenacht • Aim: Symptom relief
Last updated Apr 30, 2026 15:49 UTC
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Brain scans reveal why rejection hurts more for some
Knowledge-focused Not yet recruitingThis study looks at how the brain reacts to feeling left out in people with borderline personality disorder (BPD). Researchers will use EEG to measure brain activity while participants play a virtual ball-tossing game designed to trigger feelings of exclusion. The goal is to unde…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: Hôpital le Vinatier • Aim: Knowledge-focused
Last updated May 17, 2026 08:54 UTC
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Scientists ask: is BPD really a 'Relationship Addiction'?
Knowledge-focused Not yet recruitingThis study tests a new idea: that borderline personality disorder (BPD) may be a form of addiction to relationships. Researchers will compare 194 people with BPD, bipolar disorder, and healthy volunteers using questionnaires and brain-related tests. The goal is to better understa…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated May 17, 2026 08:47 UTC
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New study links menstrual cycle to emotional swings in autistic women
Knowledge-focused Not yet recruitingThis study looks at how emotions change throughout the menstrual cycle in autistic women. Researchers will compare them to women with borderline personality disorder, premenstrual dysphoric disorder, and those without any condition. The goal is to better understand emotional ups …
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC