BACTERIAL INFECTIONS

This study tested a radioactive tracer called 11C-PABA to see if it can help doctors find infections deep inside the body using PET scans. Researchers studied 13 healthy people and patients with infections, inflammatory diseases, or cancer. The goal was to see if this tracer can …

This study looked at blood samples from 394 people with high fever to find protein patterns that can tell if an infection is bacterial or viral. Researchers used artificial intelligence to analyze the proteins and check how accurate they are. The goal is to create a simple blood …

This study tested a new, easy-to-use blood culture system called BactInsight in hospitals in Benin and Burkina Faso. The goal was to see if it can diagnose bloodstream infections faster and more reliably than current methods. If successful, it could help doctors use antibiotics m…

This study tested whether giving mothers a single 2-gram dose of the antibiotic azithromycin during labour (or just before a C-section) could reduce the number of skin and soft tissue infections in their babies by 3 months of age. Over 2,100 pregnant women participated. The appro…

This study tested whether a special probiotic (Bifidobacterium breve PRL2020) could reduce diarrhea and other stomach issues in 121 children aged 3-12 who were taking common antibiotics. The probiotic was given alongside the antibiotics to see if it could protect the gut's health…

This study tested a new imaging technique using a radioactive tracer called 11C-trimethoprim to see how it spreads in the bodies of 16 adults with suspected bacterial infections. Participants had PET/CT scans to track the tracer over time. The goal was to learn how the tracer beh…

This early-stage study tested the safety and how the body processes two antibiotics (cefiderocol and xeruborbactam) given together. It involved 60 healthy adults aged 18-55. The goal was to check for side effects and measure drug levels, not to treat any disease.

This early-stage study tested a new oral drug (QPX7831) combined with an antibiotic (ceftibuten) in 53 healthy adults aged 18-55. The goal was to check safety and how the drugs interact in the body, not to treat any disease. Results will help design future studies for bacterial i…

This study looks at why certain drugs, like the antifungal voriconazole and the antibiotic doxycycline, can cause an exaggerated sunburn reaction called phototoxicity. Researchers will measure gene activity in skin samples from 62 participants (ages 8 and up) to better understand…

This study looked at how a single dose of the antibiotic omadacycline works in children (ages 8 to under 18) who were hospitalized with a bacterial infection. Researchers measured drug levels in the blood and checked for side effects. The goal was to gather information, not to tr…