BACTERIAL INFECTIONS

This study tests a new vaccine designed to protect healthy infants from pneumococcal infections, which can cause pneumonia, meningitis, and other serious illnesses. About 600 babies in Thailand will receive either the new vaccine or an existing one to compare safety and immune re…

This study tests whether adding XEMBIFY (an antibody replacement) to standard treatment can reduce serious bacterial infections in adults with certain blood cancers (chronic lymphocytic leukemia, multiple myeloma, or non-Hodgkin lymphoma) who have low antibody levels and frequent…

This early-phase study is testing a radioactive tracer called [18F]F-TMP to see how it spreads in the body and whether it can help detect bacterial infections using PET/CT scans. About 20 adults with known or suspected bacterial infections will receive the tracer and undergo imag…

This study looks at how people recover after infective endocarditis, a serious heart infection. Researchers want to see if a 12-week exercise program can improve physical fitness, fatigue, and quality of life. About 50 adults who had the infection will take surveys, do interviews…

This study is enrolling 2000 adults who come to the emergency department with a suspected respiratory infection. Researchers will collect blood and other samples to build a biobank and analyze the body's response to different germs. The goal is to discover better ways to diagnose…

This early-stage study is testing a new drug called JKN2501 in 66 healthy adults in China. The goal is to see if the drug is safe and how the body processes it, not to treat any disease. Participants will receive either the drug or a placebo by IV, and researchers will monitor fo…

This study looks at how well beta-lactam antibiotics work in people with liver cirrhosis and bacterial infections. Researchers will review past cases and follow new patients to build a model that predicts the best dose for each person. The goal is to lower death rates by tailorin…

This study is observing how children with meningitis are treated in hospitals across Brazil and how they recover over time. It will include 600 children under 18 with suspected meningitis. The goal is to learn what works best and where care can be improved, without testing any ne…

This early-stage study is testing a new antibiotic called Cefiderocol/Xeruborbactam in 40 adults with different levels of kidney function, including those on dialysis. The main goal is to see how safe the drug is and how the body processes it. Participants receive a single dose o…