B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Clinical trials for B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA explained in plain language.
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New CAR-T 'Sandwich' strategy aims to stop leukemia relapse
Disease control TerminatedThis study tests a new treatment plan for young adults and adults with B-cell acute lymphoblastic leukemia (B-ALL). The approach combines immunotherapy before a stem cell transplant, followed by a "sandwich" of two types of CAR-T cell therapy (targeting CD22 and CD19) after the t…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Disease control
Last updated Jun 17, 2026 01:29 UTC
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Engineered immune cells offer new hope for Hard-to-Treat leukemia
Disease control OngoingThis study tests a treatment that uses a patient's own immune cells, modified to target and kill leukemia cells. It is for people with B-cell acute lymphoblastic leukemia that has not responded to standard treatments or has come back. The goal is to see if this therapy can put th…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Disease control
Last updated Jun 16, 2026 12:54 UTC
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Double-barreled cell therapy aims to beat leukemia relapse
Disease control OngoingThis study tests a new treatment for B-cell acute lymphoblastic leukemia that combines two types of CAR-T cells (targeting CD22 and CD19) with a stem cell transplant using the patient's own cells. The goal is to lower the chance of the cancer coming back after treatment. 37 parti…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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New cell therapy aims to wipe out stubborn leukemia in kids
Disease control OngoingThis study tests a treatment called tisagenlecleucel (a type of CAR-T cell therapy) in children and young adults aged 1 to 25 with high-risk B-cell acute lymphoblastic leukemia. Participants have cancer cells still present after initial chemotherapy. The treatment uses the patien…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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New combo therapy aims to boost leukemia fight without harming transplant
Disease control OngoingThis early-stage trial tests whether giving specially engineered donor immune cells (CAR T cells) after a stem cell transplant is safe for adults with a high-risk type of B-cell leukemia. About 22 participants will receive the treatment to see if it can help prevent the cancer fr…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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Engineered immune cells take on Hard-to-Treat blood cancers
Disease control OngoingThis early-phase study tests an experimental therapy called NKX019 for people with certain blood cancers (like lymphoma and leukemia) that have come back or not responded to other treatments. NKX019 uses donor immune cells (natural killer cells) that are specially designed to fin…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Nkarta, Inc. • Aim: Disease control
Last updated Jun 10, 2026 13:26 UTC
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New drug combo shows promise in early trial for tough blood cancer
Disease control OngoingThis early-phase study tests whether combining two drugs, venetoclax and inotuzumab ozogamicin, is safe and effective for people with B-cell acute lymphoblastic leukemia (B-ALL), a fast-growing blood cancer. About 23 adults whose cancer has returned or not responded to treatment …
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Jun 09, 2026 12:08 UTC
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Boosting CAR t: early second dose may keep childhood leukemia at bay
Disease control OngoingThis study tests whether giving a second dose of the CAR T-cell therapy tisagenlecleucel early can keep the immune system's B cells low for at least 6 months in children and young adults with relapsed B-cell acute lymphoblastic leukemia. The goal is to reduce the chance of the ca…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 08, 2026 13:09 UTC
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New hope for older leukemia patients: targeted drug plus gentle chemo
Disease control OngoingThis study tests a new treatment for older or medically frail adults with B-cell acute lymphoblastic leukemia (a fast-growing blood cancer). The treatment combines a targeted drug (blinatumomab, given as a shot under the skin) with low-intensity chemotherapy. The goal is to see i…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 08, 2026 13:08 UTC