New CAR-T 'Sandwich' strategy aims to stop leukemia relapse

NCT ID NCT06985498

First seen Mar 28, 2026 · Last updated Jun 16, 2026 · Updated 7 times

Summary

This study tests a new treatment plan for young adults and adults with B-cell acute lymphoblastic leukemia (B-ALL). The approach combines immunotherapy before a stem cell transplant, followed by a "sandwich" of two types of CAR-T cell therapy (targeting CD22 and CD19) after the transplant. The goal is to reduce the chance of the cancer coming back. The study is currently suspended and aims to enroll 40 participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • The First Affiliated Hospital of Soochow University

    Suzhou, China

Conditions

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Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.