ASTHMA (DIAGNOSIS)

This study looks at the long-term safety and effectiveness of an oral drug called KT-621 in people with asthma. Participants have already completed a previous KT-621 asthma study. The goal is to see how well the drug works over time and if any side effects appear with longer use.

This study tests a dog allergy immunotherapy called Alutard SQ Dog in 40 adults with moderate-to-severe dog allergy. Participants receive increasing doses over 13 weeks, then maintenance shots every 6-8 weeks for a year. Their symptoms and lung function are measured before and af…

This study tests whether a single dose of a nasal spray called ETH47 can reduce asthma symptoms caused by a common cold virus (rhinovirus). Fifty adults with stable asthma will receive either the spray or a placebo and then be exposed to the virus in a controlled setting. Researc…

This study is testing a mobile app called Adhera Caring Digital Program for Obesity (ACDP-O) in 280 families. The app provides personalized education, mental health monitoring, and wearable device integration to support weight management and well-being in adolescents and young ad…

This study tests whether astaxanthin, a natural antioxidant supplement, can improve lung function and reduce airway inflammation in adults with mild-to-moderate asthma. Participants will take astaxanthin and a placebo in random order for 4 weeks each, with a break in between. The…

This study is enrolling 200 adults with asthma or COPD to see if combining chest CT scans with blood, sputum, and microbiome tests can more accurately tell the two diseases apart. Researchers will also look for clues that predict how well a patient will respond to treatment. No e…

This study compares two types of aerobic exercise for children with asthma: virtual reality-based games and treadmill walking. Thirty children aged 10-17 will exercise twice a week for 8 weeks. Researchers will measure lung function, exercise capacity, and quality of life to see …

This study compares two breathing exercises—alternate nostril breathing and Buteyko breathing—in 46 adults with mild to moderate asthma. The goal is to see which technique better improves breath control, reduces shortness of breath, and boosts lung function. Participants will pra…

This study is testing whether a structured exercise program called Indonesian Asthma Gymnastic can help adults with stable asthma breathe better and feel better day-to-day. Researchers will measure walking distance, lung function, and asthma control in 35 participants who continu…

This study looks at whether watching a short, AI-created story video at home can help children aged 4 to 10 feel less anxious and scared before their first skin prick test for allergies. About 100 kids will be split into two groups: one watches the video, the other gets standard …

This study tests a smartphone system called ReACT that helps teens ages 13-17 with poorly controlled asthma. The app tracks medication use and symptoms, and offers personalized tips and goal-setting. 160 teens will be randomly assigned to use ReACT or a basic asthma app for six m…

This study aims to understand why breathlessness varies among people with different lung diseases like COPD, asthma, and ILD. Researchers will measure lung function, exercise ability, and breathing patterns in 75 participants (50 with lung disease and 25 healthy controls). The go…

This study looks at whether treating obstructive sleep apnea (OSA) with a CPAP machine can improve asthma control in people with difficult-to-treat asthma. Eighty adults will be randomly assigned to receive CPAP, no OSA treatment, or serve as a reference group without OSA. The go…

This study looks at how body composition (like weight and fat distribution) relates to airway tone and reactivity. Researchers will use a device called an oscillometer to measure airway resistance in 100 people who are already scheduled for a methacholine challenge test. The goal…

People with serious mental illness often have undiagnosed physical conditions like heart disease, diabetes, and cancer. This study tests whether adding routine physical health checks to psychiatric care helps find and treat these hidden illnesses. About 2,800 adults in Denmark wi…

This study looks at how the immune system influences disease control in people with inflammatory airway diseases like asthma, COPD, and bronchiectasis. Researchers will analyze blood and sputum samples from 200 participants to find links between immune cell patterns and disease s…

This observational study is investigating how patients with chronic airway diseases like COPD and asthma perceive breathing difficulty. Researchers will assess about 950 participants (800 patients and 150 healthy volunteers) using questionnaires, lung function tests, blood sample…

This study looks back at medical records of about 59 ICU patients who used a low-flow carbon dioxide removal (ECCO2R) machine for breathing failure. The goal is to describe how the device was used and what happened to patients, including survival and side effects. It does not tes…

This study follows 250 adults with asthma over about 5 years to see how the disease varies from person to person and changes over time. Researchers will track lung function, symptoms, triggers, and flare-ups through annual clinic visits and home assessments. The goal is to better…