ASTHMA (DIAGNOSIS)

This study tests a new drug, linvemastat, for adults with moderate-to-severe asthma that is not fully controlled by standard inhalers. About 135 participants will receive either one of two doses of linvemastat or a placebo, while continuing their usual medications. Over 16 weeks,…

This study evaluates a portable device that measures lung function using oscillometry—a technique that sends gentle sound waves into the lungs—to diagnose chronic respiratory diseases like COPD, asthma, and bronchiectasis. Researchers will enroll about 4,000 adults across 50 cent…

This study will collect cough sounds, breath sounds, and symptom questionnaires from 1,400 children with respiratory symptoms like cough or fever. Researchers will use this data to build a computer model that can help diagnose conditions like asthma and pneumonia. The goal is to …

This study is testing a new, easy way to diagnose asthma and COPD using a handheld device that measures carbon dioxide in a person's breath. Instead of the current uncomfortable and time-consuming lung tests, participants simply breathe normally into the device for 75 seconds. Th…

This study tests whether wearing a special LED vest for 20 minutes twice a week can improve lung function and exercise ability in children aged 6 to 17 with mild to moderate asthma. The vest uses light to reduce inflammation without heat. Half the children will get the active ves…

This study tests whether acupuncture can help people with mild-to-moderate chronic asthma breathe better and feel less anxious or depressed. 180 adults will be randomly assigned to real acupuncture, fake acupuncture, or usual care. The main goal is to see if real acupuncture impr…

This pilot study tests whether anakinra, a drug that reduces inflammation, can help people with moderate asthma attacks. 60 adults at high risk for asthma attacks will either receive anakinra or a placebo at home when they feel an attack starting. The study will check if this app…

This study compares two common steroids (dexamethasone and methylprednisolone) in children aged 3-17 hospitalized for severe asthma. The goal is to see which treatment reduces the need for more steroids after leaving the hospital and improves quality of life. The trial will help …

This study tests a new digital program designed to help people with moderate to severe asthma manage breathlessness and increase physical activity. Researchers will compare the program to usual care in 300 adults. The goal is to see if the program improves quality of life and ast…

This study compares two types of inhalers—pressurized metered dose inhalers (pMDI) and dry powder inhalers (DPI)—to see which delivers asthma medication more effectively. Researchers will enroll 210 patients with uncontrolled asthma and measure changes in symptom control after 8 …

This early-stage trial tests a single oral dose of ADO-5030 in 36 adults with mild-to-moderate asthma. Researchers will check safety and how the drug affects breathing during a controlled airway challenge. The goal is to gather initial data, not to prove the drug works yet.

This study will ask 460 teenagers with asthma in China to fill out questionnaires about their asthma control, anxiety, depression, and self-care skills. The goal is to understand how mental health and disease management are connected in this age group. No new treatments or medica…