ANGIOSARCOMA

This study is testing if taking a drug called regorafenib for up to a year can help prevent bone cancers (sarcomas) from returning after patients finish their initial chemotherapy and surgery. It will compare patients who take the drug to those who receive standard monitoring wit…

This study is testing a combination of chemotherapy drugs (ifosfamide, doxorubicin), a targeted drug (pazopanib), and sometimes a newer drug (selinexor) and radiation therapy for young patients (up to age 30) with rare soft tissue cancers. The goal is to see if this approach can …

This is the first study in people testing a new cancer drug called AGX101. It aims to find a safe and effective dose for patients with advanced solid tumors that have spread or cannot be removed by surgery, and who have no other standard treatment options left. The drug is given …

This study is testing a new two-part treatment for advanced angiosarcoma, a rare and aggressive cancer. It combines a modified virus injected directly into tumors with a standard immunotherapy drug. The goal is to see if this combination is safe and can shrink tumors in patients …

This is an early-stage study to find a safe dose of an experimental therapy called MQ710 for people with advanced solid tumors that have returned, spread, or stopped responding to standard treatments. The therapy is a modified virus designed to be injected directly into tumors. R…

This trial aims to find the best drug combinations for different types of breast cancer before surgery. It tests new drugs alongside standard chemotherapy in 5,000 women with early-stage or locally advanced breast cancer. The study uses tumor analysis and MRI scans to match treat…

This study is testing whether adding a new immunotherapy drug called tislelizumab to standard chemotherapy works better for people with advanced soft tissue sarcoma. It will enroll 45 adults with specific types of sarcoma that cannot be removed by surgery or have spread. The main…

This study aims to understand how personalized chemotherapy before surgery works for high-risk sarcoma patients. Researchers will collect tissue samples from 800 patients who either receive chemotherapy before surgery or go directly to surgery. By analyzing these samples, they ho…

This study aims to gather detailed information on patients with localized angiosarcoma, a rare and aggressive cancer. It will follow 250 patients across multiple Italian hospitals as they receive standard care. The goal is to better understand the disease's characteristics and ho…