New hope for rare childhood cancer: drug cocktail aims to shrink tumors and prevent return
NCT ID NCT06239272
First seen Nov 16, 2025 · Last updated Jun 17, 2026 · Updated 34 times
Summary
This study is for children and young adults (up to age 30) with a rare type of soft tissue cancer called non-rhabdomyosarcoma. It tests whether adding the drugs pazopanib and selinexor to standard chemotherapy can improve outcomes. Participants receive treatment tailored to their risk level, and some also get targeted radiation. The goal is to control the disease and prevent it from coming back.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Healthcare of Atlanta
NOT_YET_RECRUITINGAtlanta, Georgia, 30329, United States
Contact
Contact
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229, United States
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact
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Lurie Children's Hospital of Chicago
RECRUITINGChicago, Illinois, 60611, United States
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Our Lady of the Lake Children's Hospital
RECRUITINGBaton Rouge, Louisiana, 70809, United States
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St. Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 38105, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Washington University Medical Center
RECRUITINGSt Louis, Missouri, 63110, United States
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.