Breast cancer trial aims to match drugs to tumors for personalized care

NCT ID NCT01042379

Recruiting now Knowledge-focused Sponsor: QuantumLeap Healthcare Collaborative Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing new drug combinations for breast cancer to see which ones work best for different tumor types. It involves up to 5,000 people with early-stage or locally advanced breast cancer. Researchers use MRI scans and tissue samples before surgery to predict treatment success and personalize care.

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Conditions

The condition(s) this trial relates to.

angiosarcoma breast cancer breast neoplasm HER2 positive breast carcinoma Her2-receptor negative breast cancer neoplasm Pathologic Complete Response triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANGIOSARCOMA BREAST CANCER BREAST NEOPLASMS BREAST TUMORS EARLY-STAGE BREAST CANCER HER2-NEGATIVE BREAST CANCER HER2-POSITIVE BREAST CANCER HORMONE RECEPTOR NEGATIVE TUMOR HORMONE RECEPTOR POSITIVE TUMOR LOCALLY ADVANCED BREAST CANCER TNBC - TRIPLE-NEGATIVE BREAST CANCER

Contacts and locations

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Locations

City of Hope
RECRUITING

Duarte, California, 91010, United States
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44106, United States
Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States
Georgetown University Medical Center
RECRUITING

Washington D.C., District of Columbia, 20007, United States
H. Lee Moffitt Cancer Center and Research Institute
RECRUITING

Tampa, Florida, 33612, United States
HOAG Memorial Hospital Presbyterian
RECRUITING

Newport Beach, California, 92663, United States
Herbert-Herman Cancer Center, Sparrow Hospital
RECRUITING

Lansing, Michigan, 48912, United States
Huntsman Cancer Institute, University of Utah
RECRUITING

Salt Lake City, Utah, 84112, United States
Inova Health System
ACTIVE_NOT_RECRUITING

Falls Church, Virginia, 22042, United States
Laura and Isaac Perlmutter Cancer Center / NYU Langone Health
RECRUITING

New York, New York, 10016, United States
Loyola University
RECRUITING

Maywood, Illinois, 60153, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Mayo Clinic - Scottsdale
NOT_YET_RECRUITING

Scottsdale, Arizona, 85259, United States
Metro Minnesota Community Oncology Research Consortium, Hennepin County Medical Center
RECRUITING

Saint Louis Park, Minnesota, 55416, United States
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
Montefiore Medical Center
RECRUITING

The Bronx, New York, 10467, United States
Oregon Health & Science Institute (OHSU)
RECRUITING

Portland, Oregon, 97239, United States
Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 14263, United States
Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08903, United States
Sanford Clinical Research
RECRUITING

Sioux Falls, South Dakota, 57104, United States
Swedish Cancer Institute
ACTIVE_NOT_RECRUITING

Seattle, Washington, 98104, United States
The Ohio State University, Stefanie Spielman Comprehensive Breast Center
RECRUITING

Columbus, Ohio, 43212, United States
University Pittsburgh Medical Center
ACTIVE_NOT_RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35294, United States
University of Arizona
ACTIVE_NOT_RECRUITING

Tucson, Arizona, 85724, United States
University of California - Davis, Comprehensive Cancer Center
RECRUITING

Davis, California, 95817, United States
University of California San Diego
RECRUITING

La Jolla, California, 92093-0698, United States

Contact Email: •••••@•••••
University of California San Francisco (UCSF)
RECRUITING

San Francisco, California, 94115, United States
University of Chicago
RECRUITING

Chicago, Illinois, 60453, United States
University of Colorado Cancer Center
RECRUITING

Aurora, Colorado, 80045, United States
University of Kansas
ACTIVE_NOT_RECRUITING

Westwood, Kansas, 66205, United States
University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States
University of Pennsylvania (U Penn)
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Rochester Wilmot Cancer Institute
RECRUITING

Rochester, New York, 14642, United States

Contact Email: •••••@•••••
University of Southern California
RECRUITING

Los Angeles, California, 90033, United States
University of Texas, M.D. Anderson Cancer Center
ACTIVE_NOT_RECRUITING

Houston, Texas, 77230-1439, United States
University of Texas, Southwestern Medical Center
ACTIVE_NOT_RECRUITING

Dallas, Texas, 75390-9155, United States
University of Washington
ACTIVE_NOT_RECRUITING

Seattle, Washington, 98115, United States
Vanderbilt University Medical Center
ACTIVE_NOT_RECRUITING

Nashville, Tennessee, 27204, United States
Wake Forest Baptist Comprehensive Cancer Center
RECRUITING

Winston-Salem, North Carolina, 27157, United States
Winship Cancer Institute of Emory University
RECRUITING

Atlanta, Georgia, 30322, United States
Yale Cancer Center
RECRUITING

New Haven, Connecticut, 06510, United States

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