ANATOMIC STAGE I BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE I BREAST CANCER AJCC V8 explained in plain language.
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New drug cocktail aims to keep breast cancer at bay
Disease control OngoingThis study tests whether adding tucatinib to the standard drug T-DM1 can better prevent HER2-positive breast cancer from returning after initial treatment. About 1,056 people with early-stage HER2-positive breast cancer who still have cancer cells after initial therapy will take …
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 16, 2026 12:54 UTC
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Radiation before surgery may improve breast cancer outcomes
Disease control OngoingThis study looks at whether giving an extra dose of radiation to the tumor before breast cancer surgery is safe and helpful. About 103 people with early-stage breast cancer that hasn't spread will take part. The goal is to see if this approach reduces side effects and leads to be…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Jun 15, 2026 19:07 UTC
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Robots help surgeons remove breast cancer while saving the nipple
Disease control OngoingThis small pilot study tested whether a robot-assisted surgical system (da Vinci) can safely perform nipple-sparing mastectomy in 4 people with early-stage breast cancer or those needing preventive mastectomy. The goal was to see if the robot could remove all breast tissue throug…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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Proton vs X-Ray: which radiation causes fewer side effects in breast cancer?
Disease control OngoingThis study compares two types of radiation therapy—standard x-ray and proton beam—for people with breast cancer who have had surgery. The goal is to see which method causes fewer serious side effects or unplanned surgeries over two years. About 146 adults with stage I to III brea…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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Texts and calls boost breast cancer Pill-Taking in major trial
Disease control OngoingThis study tests whether adding text message reminders and/or telephone counseling helps breast cancer patients take their daily hormone therapy pills more consistently. About 1,167 women with early-stage, hormone-sensitive breast cancer will be followed for up to two years. The …
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 12, 2026 12:04 UTC
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Can fasting plus a diabetes drug shrink breast tumors?
Disease control OngoingThis study looks at whether combining a nightly fasting period with the diabetes drug metformin can reduce breast cancer cell growth in women with early-stage invasive breast cancer or ductal carcinoma in situ (DCIS). About 120 participants will follow a fasting schedule and take…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 10, 2026 13:24 UTC
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Could less be more? new trial reduces breast cancer treatment for top responders
Disease control OngoingThis study is for people with early HER2-positive or triple-negative breast cancer whose tumors completely disappeared after initial treatment before surgery. Researchers want to see if giving less therapy after surgery can still keep the cancer away while reducing side effects. …
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 02, 2026 11:58 UTC
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New study aims to keep young breast cancer patients on lifesaving pills
Symptom relief OngoingThis study tests whether regularly checking in on symptoms, along with providing educational materials, helps young women with early-stage breast cancer continue taking their hormone therapy as prescribed. Hormone therapy can cause unpleasant side effects, leading some to stop ea…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: SWOG Cancer Research Network • Aim: Symptom relief
Last updated Jun 15, 2026 19:06 UTC
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New web tool aims to ease symptoms for young breast cancer survivors
Symptom relief OngoingThis study tests a web-based portal called YES that helps young breast cancer survivors track symptoms and find self-management resources. About 400 women aged 15-39 with early-stage breast cancer are taking part. The goal is to see if using the portal improves quality of life co…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 15, 2026 19:03 UTC
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New program aims to boost quality of life for seniors after breast cancer
Symptom relief OngoingThis study tests a special check-up and support program for adults 65 and older who have finished treatment for early-stage breast cancer. The goal is to improve their overall health and quality of life by addressing physical, mental, and emotional needs. Participants will comple…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 15, 2026 19:03 UTC
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Walking through chemo: new study tests exercise for older breast cancer patients
Symptom relief OngoingThis study looks at whether a regular exercise program is practical for women aged 65 and older who are receiving chemotherapy for early-stage breast cancer. Participants will be asked to walk and do arm exercises several times a week. The goal is to see if exercise can reduce th…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 15, 2026 18:57 UTC
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Hypnosis may replace general anesthesia in breast cancer surgery
Symptom relief OngoingThis study looks at whether hypnosis can help women with early-stage breast cancer relax during surgery and reduce the need for general anesthesia. About 50 women will try hypnosedation, a technique that uses words and images to keep them calm and awake while numb. The goal is to…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 15, 2026 18:56 UTC
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Can a digital kitchen program help breast cancer survivors eat healthier?
Symptom relief OngoingThis study tests a remote program that combines mindfulness with nutrition and cooking lessons to help breast cancer survivors eat better. About 49 people who had stage I-III breast cancer in the past 5 years will take part. The program is delivered online through the Cook for Yo…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Symptom relief
Last updated Jun 12, 2026 12:07 UTC
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Can yoga and nutrition help breast cancer survivors feel better? a new study aims to find out.
Symptom relief OngoingThis study looks at whether two different health programs are practical and liked by breast cancer survivors. About 106 people who finished treatment for early-stage breast cancer will try either an Ayurveda program (with diet, yoga, and touch therapy) or a self-guided online edu…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 12, 2026 12:07 UTC
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Writing away the pain: new study tests expressive writing for chinese breast cancer survivors
Symptom relief OngoingThis study looks at whether a culturally tailored writing program can improve the well-being of Chinese immigrant women who had breast cancer (stages 0 to III). About 256 women who finished their main cancer treatment in the last 5 years will write about their experiences. The go…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 02, 2026 11:57 UTC
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Picture this: a simple tool to ease breast cancer radiation stress
Symptom relief OngoingThis study looks at whether adding a picture guide to standard counseling can lower anxiety and depression in women with early-stage breast cancer who are about to start radiation therapy. About 62 women will take part, and researchers will compare their stress levels using quest…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Symptom relief
Last updated Jun 01, 2026 18:02 UTC
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Cancer survivors share fertility hopes in new survey
Knowledge-focused OngoingThis study surveys women aged 18-45 who have had gynecological or breast cancer to learn how they think about having children after treatment. Researchers will use the survey results to better understand fertility concerns and help future patients make informed decisions about ca…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 16, 2026 23:23 UTC
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Gene test may guide breast cancer therapy choices
Knowledge-focused OngoingThis study looks at whether a genetic test on tumor samples can predict how well HER2-negative breast cancer will respond to standard treatments like chemotherapy or hormone therapy. About 1,100 people with stage I-III breast cancer are taking part. The goal is to see if this tes…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:48 UTC
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Genetic test may predict chemo nerve pain in black women
Knowledge-focused OngoingThis study looks at whether a genetic test can identify African American women with breast cancer who are more likely to develop nerve damage from chemotherapy drugs like docetaxel or paclitaxel. About 249 women with stage I-III breast cancer will be enrolled. The goal is to see …
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:05 UTC
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Blood test could spot hidden cancer cells after breast cancer surgery
Knowledge-focused TerminatedThis study looks at whether a blood test can find tiny amounts of cancer DNA left in the body after treatment for early-stage breast cancer. About 350 patients with stage I to III breast cancer will give blood samples to see if the test can help doctors decide who needs more ther…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:08 UTC
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New study aims to help older breast cancer patients make chemo choices
Knowledge-focused OngoingThis study looks at how women aged 65 and older with early-stage breast cancer make decisions about chemotherapy. Researchers will interview patients and doctors to understand what information they need. The goal is to create a simple tool that helps patients and doctors weigh th…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:10 UTC
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Can we predict who will get nerve damage from chemo?
Knowledge-focused OngoingThis study aims to find out why some cancer patients develop nerve damage (tingling or numbness in hands and feet) from taxane chemotherapy. Researchers will track over 1,300 people with breast, lung, or ovarian cancer to see how age, gender, and other factors affect their risk. …
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Sponsor: SWOG Cancer Research Network • Aim: Knowledge-focused
Last updated Jun 03, 2026 12:04 UTC