ALCOHOL USE DISORDER (AUD)
Clinical trials for ALCOHOL USE DISORDER (AUD) explained in plain language.
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New shot could curb heavy drinking in overweight adults
Disease control OngoingThis study tests a weekly injection called pemvidutide in 100 overweight or obese adults with moderate-to-severe alcohol use disorder. The goal is to see if it reduces the number of heavy drinking days compared to a placebo. Participants receive either the drug or a placebo for 2…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Phase: PHASE2 • Sponsor: Altimmune, Inc. • Aim: Disease control
Last updated May 17, 2026 00:59 UTC
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Sound waves against addiction: new ultrasound therapy targets alcohol cravings
Disease control OngoingThis study tests whether a non-invasive ultrasound treatment can lower cravings and help prevent relapse in people with alcohol use disorder. Forty adults will receive either real or fake (sham) ultrasound stimulation to the brain. The goal is to see if this safe, painless techni…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Phase: NA • Sponsor: Shanghai Mental Health Center • Aim: Disease control
Last updated May 08, 2026 12:02 UTC
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Ketone supplement trial aims to map brain-heart energy link in alcohol use disorder
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how a single dose of a ketone ester supplement changes glucose use in the brain and heart of people with and without alcohol use disorder. Twenty adults (10 with AUD, 10 healthy) will receive either the supplement or a placebo, then have a PET/CT scan. The goa…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Phase: PHASE2, PHASE3 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 17, 2026 00:48 UTC
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Why some people beat alcohol addiction in group therapy while others Don't – new study investigates
Knowledge-focused OngoingThis study follows 120 people in group therapy for alcohol use disorder to see which patient traits predict success. Researchers will track factors like mental health, drinking severity, personality disorders, and cognitive issues to find out who completes treatment and stays sob…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Sponsor: The Hospital of Vestfold • Aim: Knowledge-focused
Last updated May 17, 2026 00:47 UTC
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Non-Alcoholic beer as a recovery tool? stanford tests the idea
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether giving non-alcoholic beers to people being treated for alcohol use disorder is something they like and can stick with. About 60 adults in California who are already in a treatment program will receive non-alcoholic beers for 6 weeks. Researchers will a…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated May 12, 2026 13:40 UTC
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Daily diaries reveal how AA really works
Knowledge-focused OngoingThis study looks at how Alcoholics Anonymous (AA) helps people with alcohol use disorder reduce their drinking. Researchers will track 192 adults daily for six months to see which AA activities—like social support or spiritual practices—lead to fewer drinks. The goal is to unders…
Matched conditions: ALCOHOL USE DISORDER (AUD)
Sponsor: University of New Mexico • Aim: Knowledge-focused
Last updated May 11, 2026 20:40 UTC