Could a seizure drug curb alcohol cravings? new trial investigates
NCT ID NCT05134857
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This phase 2 trial tests whether zonisamide, a drug currently used for seizures, can help adults with alcohol use disorder drink less. About 205 treatment-seeking participants will receive either zonisamide or a placebo, along with standard support. The study measures alcohol consumption through self-reports and breathalyzer tests over 14 weeks of treatment and follow-up.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
zonisamide
What this could lead to
If successful, this could provide a new medication option to help people with alcohol use disorder drink less.
What could go wrong
This is a phase 2 trial, so it is still early. The drug may not work better than placebo, and side effects like dizziness or drowsiness are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Other studies related to the condition(s) this trial covers.
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Contacts and locations
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Locations
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Washington State University
Spokane, Washington, 99202, United States