AL AMYLOIDOSIS
Clinical trials for AL AMYLOIDOSIS explained in plain language.
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New study tailors amyloidosis therapy based on genetic marker
Disease control Recruiting nowThis study tests a personalized approach for people newly diagnosed with AL amyloidosis who have a specific genetic change called t(11;14). All participants start with a standard three-drug combination. If their blood responds quickly within 7 days, they continue that treatment; …
Matched conditions: AL AMYLOIDOSIS
Phase: NA • Sponsor: Jin Lu, MD • Aim: Disease control
Last updated May 01, 2026 16:01 UTC
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New hope for AL amyloidosis patients: experimental drug elranatamab under study
Disease control Recruiting nowThis study tests an experimental drug called elranatamab in people with AL amyloidosis whose disease has returned or not responded to prior treatment. The goal is to find the safest and most effective dose and to see how well the drug controls the disease. About 49 participants w…
Matched conditions: AL AMYLOIDOSIS
Phase: PHASE1, PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 01, 2026 16:01 UTC
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Can longer treatment keep amyloidosis at bay? new trial investigates
Disease control Recruiting nowThis study looks at whether taking daratumumab for a longer time after initial treatment helps people with AL amyloidosis live longer without the disease coming back. About 96 adults who have already responded to daratumumab will be assigned to either shorter or longer maintenanc…
Matched conditions: AL AMYLOIDOSIS
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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New italian network aims to catch rare disease early
Diagnosis Recruiting nowThis study connects Italian hospitals to a specialized center to find AL amyloidosis earlier. Researchers will screen 760 people with related blood conditions using new biomarker tests. The goal is to speed up diagnosis and treatment, and to learn more about the disease.
Matched conditions: AL AMYLOIDOSIS
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Diagnosis
Last updated May 01, 2026 15:58 UTC
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New european network aims to crack the code of rare amyloidosis
Knowledge-focused Recruiting nowThis study is creating a large European registry of 400 people newly diagnosed with AL amyloidosis, a rare disease where abnormal proteins build up in organs. Researchers will collect medical data and blood samples to study the disease using advanced technology. The goal is to im…
Matched conditions: AL AMYLOIDOSIS
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated May 01, 2026 15:56 UTC
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One gene, two diseases: scientists uncover clues to rare blood disorders
Knowledge-focused Recruiting nowThis study looks at how a specific gene (IGLV1-44) leads to two rare diseases: AL amyloidosis and POEMS syndrome. Researchers will analyze blood and bone marrow samples from 100 adults with these conditions or multiple myeloma. The goal is to find unique genetic patterns that cou…
Matched conditions: AL AMYLOIDOSIS
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:49 UTC