AL AMYLOIDOSIS

This study tested a combined bone marrow and kidney transplant from a partially matched family donor for 10 people with both a serious blood disorder and chronic kidney disease. The goal was to treat both conditions while lowering the risk of kidney rejection and reducing the nee…

This study tested a drug called belantamab mafodotin in 35 people with AL amyloidosis, a rare disease where abnormal proteins build up in organs. All participants had already received at least one prior treatment. The goal was to see how many patients achieved a significant reduc…

This study tested whether a special PET scan using a radioactive tracer called [18F]Florbetaben can accurately diagnose cardiac AL amyloidosis, a rare condition where abnormal proteins build up in the heart. Researchers enrolled 244 adults with suspected cardiac amyloidosis and c…

This study looked at whether advanced imaging techniques (MRI, PET, and echocardiogram) can help predict survival and measure treatment response in people with cardiac AL amyloidosis, a rare disease where abnormal proteins build up in the heart. Thirty newly diagnosed adults were…

This completed study involved 250 adults with AL amyloidosis, a rare disease where abnormal proteins damage organs. Researchers analyzed leftover blood and bone marrow samples to find biological markers that could predict how well patients respond to first-line therapies. The goa…

This study followed 37 people who carry a genetic mutation for hereditary ATTR amyloidosis but do not yet have symptoms. Over five years, researchers measured a specific misfolded protein in the blood to see if it changes when the disease starts or when treatment is given. The go…