ADVANCED MALIGNANT SOLID NEOPLASM
Clinical trials for ADVANCED MALIGNANT SOLID NEOPLASM explained in plain language.
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Scientists test new drug duo in fight against tough cancers
Disease control CompletedThis early-stage study aimed to find the safest dose of two drugs, sapanisertib and ziv-aflibercept, when given together to patients with advanced solid tumors that had stopped responding to standard treatments. The main goal was to understand the side effects and determine the h…
Matched conditions: ADVANCED MALIGNANT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:40 UTC
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Scientists combine radiation with Immune-Boosting drugs to fight spreading cancers
Disease control CompletedThis study tested whether combining targeted radiation with immune-boosting drugs could help control advanced cancers that had spread to the lungs or liver. Researchers worked with 51 patients to find safe doses and see if this approach could shrink tumors both where radiation wa…
Matched conditions: ADVANCED MALIGNANT SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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A phase II study of oral infigratinib in adult patients with advanced or metastatic solid tumors with FGFR1-3 gene fusions or other FGFR genetic alterations
CompletedThis phase II trial studies how well infigratinib works in treating solid tumors that have spread to other places in the body (advanced or metastatic) in patients with FGFR gene mutations such as FGFR1-3 gene fusions or other FGFR genetic alterations. Mutations are any changes in…
Matched conditions: ADVANCED MALIGNANT SOLID NEOPLASM
Phase: PHASE2 • Sponsor: Sameek Roychowdhury
Last updated Mar 03, 2026 14:07 UTC