New drug combo shows promise for Hard-to-Treat cancers

NCT ID NCT05038839

First seen Nov 20, 2025 · Last updated May 15, 2026 · Updated 18 times

Summary

This early-stage trial tested two drugs, cabozantinib and pamiparib, in 44 people with advanced solid tumors that had stopped responding to standard treatments. The goal was to find the safest dose and see how well the drugs worked together to block cancer cell growth. The study focused on tumors with specific genetic changes, like BRCA mutations.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.