ACUTE HYPOXEMIC RESPIRATORY FAILURE
Clinical trials for ACUTE HYPOXEMIC RESPIRATORY FAILURE explained in plain language.
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New device aims to wean ventilator patients faster
Disease control Recruiting nowThis study tests a temporary device that stimulates the diaphragm (the main breathing muscle) in ICU patients on breathing machines. The goal is to see if it helps patients breathe more on their own and recover from lung injury. About 30 adults with severe breathing failure will …
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Phase: NA • Sponsor: Lungpacer Medical Inc. • Aim: Disease control
Last updated Jul 01, 2026 23:00 UTC
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Simple Face-Down position could save lives in breathing failure
Disease control Recruiting nowThis study tests whether awake patients with acute breathing failure who lie face down (prone positioning) for at least 10 hours a day for 3 days are less likely to need a breathing tube or die within 28 days, compared to standard care. The trial will include 342 intensive care u…
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Phase: NA • Sponsor: Universitätsklinikum Hamburg-Eppendorf • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Blood marker may help doctors spot and treat respiratory failure before it worsens
Disease control Recruiting nowThis study tests whether measuring a blood marker called interleukin-6 (IL-6) can help doctors decide when to give anti-inflammatory drugs to patients hospitalized with acute respiratory failure. Patients with high IL-6 levels will receive either standard care, a single dose of t…
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Phase: PHASE2 • Sponsor: Lorenzo delSorbo • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Helmet vs. mask vs. oxygen: which keeps patients off breathing tubes?
Disease control Recruiting nowThis study tests three ways to help patients with severe low oxygen levels breathe better without needing a breathing tube. About 1,200 adults will be randomly assigned to receive either a helmet mask that pushes air, a helmet mask that keeps airways open, or high-flow oxygen thr…
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New device aims to prevent Ventilator-Induced muscle weakness
Symptom relief Recruiting nowThis study tests a new device called Heecap that uses gentle electrical stimulation to keep the breathing muscles active in ICU patients on mechanical ventilators. Many patients on ventilators develop weak breathing muscles, which can make it hard to breathe on their own later. T…
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Phase: NA • Sponsor: Tesai Care SL • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Could slower breathing on ventilators save lungs? small study aims to find out
Knowledge-focused Recruiting nowThis pilot study tests whether using a lower breathing rate on ventilators is safe and practical for critically ill patients. About 56 adults on breathing machines will be randomly assigned to either the new lower-rate approach or standard care. The goal is to see if the new meth…
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Phase: NA • Sponsor: Reinier de Graaf Groep • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Blood test may predict who needs a breathing tube
Knowledge-focused Recruiting nowThis observational study with 300 ICU patients aims to see if combining blood markers (metabolomics) with standard clinical data can better predict when high-flow nasal cannula fails, requiring a breathing tube. Researchers will collect blood samples and monitor outcomes to build…
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Sponsor: Hospital del Mar Research Institute (IMIM) • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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New index could prevent ventilator Over-Assistance in ICU patients
Knowledge-focused Recruiting nowThis study tests whether a new measure called the Pressure-Muscle Index (PMI) can help doctors set ventilators more precisely for ICU patients with acute breathing failure. The goal is to avoid giving too much breathing support, which can harm the diaphragm and lungs. Thirty-six …
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Phase: NA • Sponsor: Centre for Medical Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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New study aims to simplify ventilator care for lung failure patients
Knowledge-focused Recruiting nowThis observational study looks at 30 adults with acute respiratory failure on mechanical ventilation. Researchers want to see if a bedside device called electrical impedance tomography (EIT) can reliably guide ventilator pressure settings, compared to the current gold standard (C…
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Sponsor: Istituto Clinico Humanitas • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Oxygen sweet spot: new study aims to cut ventilator time for ICU patients
Knowledge-focused Recruiting nowThis study tests whether training ICU staff to keep oxygen levels between 90-96% helps patients on breathing machines recover faster. Researchers will track how many days patients are free from the ventilator and how often dangerously low oxygen goes unnoticed. The goal is to imp…
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Massive trial aims to find best treatments for breathing failure in ICU patients
Knowledge-focused Recruiting nowThis study is testing many different treatments for patients with severe breathing problems in the intensive care unit. It will include up to 6,250 participants and looks at various approaches like breathing machine settings, medications, and life support techniques. The goal is …
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New approach to muscle relaxants could make breathing machines safer
Knowledge-focused Recruiting nowThis study is testing a new method for giving muscle relaxants to patients with severe breathing problems who are on a breathing machine. The goal is to see if this approach is safe and possible, and if it helps patients breathe on their own more easily. About 23 adults in the ho…
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Which intubation timing is best for breathing failure? new study aims to find out
Knowledge-focused Recruiting nowThis study looks at two different approaches to deciding when to place a breathing tube in patients with acute hypoxemic respiratory failure (dangerously low oxygen levels). One strategy is more liberal (intubate earlier to prevent complications from low oxygen), while the other …
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Phase: NA • Sponsor: University Hospital, Angers • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Ventilator study aims to Fine-Tune breathing support for ICU patients
Knowledge-focused Recruiting nowThis study looks at how changing the pressure in a breathing machine (ventilator) affects the effort and drive to breathe in 20 ICU patients with severe lung failure. Researchers will test six different pressure levels and measure breathing muscles, lung activity, and oxygen leve…
Matched conditions: ACUTE HYPOXEMIC RESPIRATORY FAILURE
Phase: NA • Sponsor: Radboud University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC