Which intubation timing is best for breathing failure? new study aims to find out

NCT ID NCT07189078

First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 29 times

Summary

This study looks at two different approaches to deciding when to place a breathing tube in patients with acute hypoxemic respiratory failure (dangerously low oxygen levels). One strategy is more liberal (intubate earlier to prevent complications from low oxygen), while the other is more restrictive (wait to avoid risks of the breathing tube itself). The goal is to see which approach leads to better outcomes, such as fewer days on organ support and lower death rates. The study will enroll 200 adults in intensive care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Angers University Hospital, ICU

    RECRUITING

    Angers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Guadeloupe University Hospital, ICU

    NOT_YET_RECRUITING

    Pointe à Pitre, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Le Mans Hospital, ICU

    NOT_YET_RECRUITING

    Le Mans, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nantes University Hospital, ICU

    NOT_YET_RECRUITING

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Orléans University hospital, ICU

    NOT_YET_RECRUITING

    Orléans, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pitié-Salpétrière Hospital, Paris University Hospital, ICU

    NOT_YET_RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rennes University Hospital, ICU

    NOT_YET_RECRUITING

    Rennes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tours University Hospital, ICU

    NOT_YET_RECRUITING

    Tours, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vannes Hospital, ICU

    NOT_YET_RECRUITING

    Vannes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

acute respiratory failure respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.