Sedation may ease risky lung exam in breathless patients
NCT ID NCT00741949
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving propofol sedation during a lung exam (bronchoscopy) under noninvasive ventilation helps patients with severe breathing failure stay more comfortable and maintain oxygen levels. Forty-six adults with acute respiratory failure needing a diagnostic lung exam took part. Half received propofol sedation, half received a placebo, and researchers measured oxygen saturation, patient comfort, and procedure success.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Propofol
- What this could lead to
- If it works, this could make bronchoscopy safer and more comfortable for patients with severe breathing problems, reducing the need for a breathing tube.
- What could go wrong
- This is a small, completed Phase 3 trial with only 46 participants, so results may not apply broadly. Propofol sedation can lower blood pressure or slow breathing, which could be risky in these patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centre hospitalier Libourne
Libourne, 33505, France
-
University Hospital Bordeaux, Groupe Hospitalier Pellegrin
Bordeaux, 33076, France
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Other studies related to the condition(s) this trial covers.
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