Helmet vs. mask vs. oxygen: which keeps patients off breathing tubes?

NCT ID NCT05089695

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests three ways to help patients with severe low oxygen levels breathe better without needing a breathing tube. About 1,200 adults will be randomly assigned to receive either a helmet mask that pushes air, a helmet mask that keeps airways open, or high-flow oxygen through the nose. The goal is to see which method reduces the need for a breathing tube and helps patients recover faster.

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Conditions

The condition(s) this trial relates to.

acute respiratory failure respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gemelli

    RECRUITING

    Rome, Italy

    Contact Email: •••••@•••••