ACUTE HYPOXEMIC RESPIRATORY FAILURE

This study tests whether a simple, low-cost breathing device called Bag CPAP can help adults with sudden severe breathing failure avoid needing a breathing tube. About 250 adults in Rwanda will be randomly assigned to receive either Bag CPAP or standard oxygen therapy. The main g…

This study looks at two different ways of using a breathing machine (mechanical ventilation) in patients with severe lung failure (ARDS). The goal is to see if it's possible to run a larger study comparing letting the patient breathe on their own versus fully controlling their br…

This study looks at 180 adults with sepsis-related acute respiratory distress syndrome (ARDS), a severe lung condition. Researchers will collect fluid from the lungs and blood samples at three time points in the first 72 hours, along with breathing machine data. The goal is to id…

This study involves 2,000 adults with breathing failure who are on high-flow oxygen therapy. Researchers want to see if a step-by-step plan to reduce and stop this oxygen therapy works better than the usual approach. The goal is to help more patients come off oxygen within 5 days…

This study looks at 30 adults with acute respiratory failure who need a breathing machine. Doctors already use two methods to set the machine's pressure: a lung CT scan (which involves radiation and transport) and a safer, simpler device called electrical impedance tomography (EI…