Urolithiasis

This study is tracking 238 adults who are already scheduled to have a procedure for kidney stones or an enlarged prostate (BPH) using Boston Scientific devices. The main goal is to see how often serious side effects happen with these tools in real-world use. Researchers will also…

This study looks back at the medical records of 3000 people who had kidney stones removed using one of two new devices: the CVAC system, a steerable suction catheter, or a special suction tube called FANS. Researchers want to see how well each device clears stones and how safe th…

This study tests whether using a smaller ureteral stent (4.8 Fr instead of 7 Fr) reduces pain and discomfort after kidney stone surgery. About 100 adults who need a stent after surgery will be randomly assigned to one of the two sizes. Patients will report their pain daily until …

This study looks at whether removing a ureteral stent 3 days after kidney stone surgery is as safe and less bothersome than the usual 7 days. About 172 adults having simple stone treatment will be randomly assigned to either 3 or 7 days of stent placement. The goal is to see if a…

This study compares two common surgeries for removing kidney stones: mini-PCNL (a small incision in the back) and flexible ureteroscopy with a special suction tube. About 80 adults with kidney stones between 1 and 3 cm will be randomly assigned to one procedure. The main goal is …

This study tests a device that uses focused ultrasound to gently push kidney stones, helping them pass or relieving pain. Researchers are enrolling 172 people with kidney stones, including those waiting for treatment or recently treated. The goal is to see if the ultrasound can m…

This study compares two drugs—methocarbamol and oxybutynin—to see which works better for pain and discomfort caused by a ureteral stent placed after kidney stone surgery. About 126 adults aged 18 to 80 who have the surgery will take one of the study drugs along with standard pain…

This study compares a simple sterile water injection into the skin with intravenous morphine for relieving severe kidney stone pain. 150 adults with confirmed stones and high pain levels will receive either one or four water injections or morphine. Pain is measured over 90 minute…

This study looked at 50,000 living kidney donors in Canada to see if they are more likely to develop kidney stones years after donating, compared to similar people who never donated. Researchers used health records from 1992 to 2024 to track surgeries or hospital visits for kidne…

This study aims to identify the bacteria and fungi living in the urinary tract of people with calcium oxalate kidney stones or kidney cancer. Researchers will compare these microbial communities to those in healthy volunteers. The goal is to better understand how these tiny organ…

This study looks at how the kidneys turn a substance called glycolate into oxalate, which can form kidney stones. Fifteen healthy adults will eat a special low-oxalate diet and receive a harmless tracer to track this process. The goal is to better understand how oxalate is made i…

This study looks at whether a measurement called the stone heterogeneity index (SHI), taken from a CT scan, can predict how well shock wave lithotripsy (SWL) breaks up upper urinary tract stones in children aged 1 to 18. Researchers will follow 286 children for three months after…

This study is looking at 150 adults having a specific type of kidney stone surgery called FANS-RIRS. Researchers want to see if the results of a routine urine culture, taken before surgery, can predict whether a patient will develop a fever after the operation. The goal is to hel…

This study from Mayo Clinic looks at whether certain gene variants make people more likely to form calcium oxalate kidney stones. Researchers will compare 2,900 adults with and without a history of kidney stones, analyzing blood samples and lifestyle factors. The goal is to bette…

This observational study aims to develop a model that uses patient information, lab results, and CT scans to accurately identify uric acid urinary stones before treatment. Researchers will enroll 1,650 patients undergoing surgery for urinary stones and compare the model's predict…